Ordering Recommendation

Monitor patient adherence.

Mnemonic
CDCO FNSP
Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry

Performed

Tue, Thu, Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), Green (Sodium Heparin), Gray (Potassium Oxalate/Sodium Fluoride), or Pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 4 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Whole blood. Serum separator tubes, Light Blue (Sodium Citrate), or Plasma separator tubes. Specimens exposed to repeated freeze/thaw cycles.

Remarks
Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years

Reference Interval

Effective August 17, 2015

Drugs Covered Cutoff Concentrations
Fentanyl 0.1 ng/mL
Norfentanyl 0.1 ng/mL

Interpretive Data

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Positive cutoff:
0.1 ng/mL

For medical purposes only; not valid for forensic use.

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

80354 (Alt code: G0480)

Components
Component Test Code* Component Chart Name LOINC
2011777 Fentanyl, S/P, Quant 3636-8
2011782 Norfentanyl, S/P, Quant 11074-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Actiq
  • Duragesic
  • Durogesic
  • Fentanyl and Metabolite
  • fentanyl and norfentanyl blood levels
  • Fentore
  • Innovar
  • Instanyl
  • Ionsys
  • norfentanyl
  • Onsolis
  • pain management
  • Sublimaze
Fentanyl and Metabolite, Serum or Plasma, Quantitative