Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum Pre-dose (Trough) Draw - At a Steady State Concentration or Plasma Pre-dose (Trough) Draw - At a Steady State Concentration in Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature


Unacceptable Conditions

Citrated Plasma.


Ambient: 1 month; Refrigerated: 1 month; Frozen: 2 months


Quantitative Liquid Chromatography-Tandem Mass Spectrometry


Wed, Sat


1-8 days

Reference Interval

Therapeutic Range Not well established
Toxic Not well established

Interpretive Data

The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Therapeutic and toxic ranges are not well established. Proposed Dose-Related Range: 2 - 10 ug/mL. Adverse effects may include peripheral edema, allergic reactions, dizziness and somnolence.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

80366 (Alt code: G0480)


Component Test Code* Component Chart Name LOINC
2011610 Pregabalin, Serum or Plasma 47414-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Lyrica
Pregabalin, Serum or Plasma