Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
PREGABALIN
Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry

Performed

Wed, Sat

Reported

1-6 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Pre-dose (Trough) Draw - At a Steady State Concentration or Plasma Pre-dose (Trough) Draw - At a Steady State Concentration in Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Citrated Plasma.

Remarks
Stability

Ambient: 1 month; Refrigerated: 1 month; Frozen: 2 months

Reference Interval
Therapeutic Range Not well established
Toxic Not well established

Interpretive Data

The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Therapeutic and toxic ranges are not well established. Proposed Dose-Related Range: 2 - 10 ug/mL. Adverse effects may include peripheral edema, allergic reactions, dizziness and somnolence.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

80366 (Alt code: G0480)

Components
Component Test Code* Component Chart Name LOINC
2011610 Pregabalin, Serum or Plasma 47414-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Lyrica
Pregabalin, Serum or Plasma