Ordering Recommendation

Therapeutic monitoring for patients receiving caffeine therapy.

Mnemonic
CAFFEINE S
Methodology

Quantitative Enzyme Multiplied Immunoassay Technique

Performed

Sun-Sat

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Random or Plasma Random in Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 6 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Citrated Plasma, Serum separator tube (SST)

Remarks
Stability

Ambient: 1 week; Refrigerated: 1 week; Frozen: 2 months

Reference Interval

Effective February 21, 2017

Age 0-28 days 29 days and older
Therapeutic Range: 8-20 µg/mL Less than or equal to 20 (not well established)
Toxic: Greater than 20 µg/mL Greater than 20 µg/mL

Interpretive Data

Toxic concentrations may cause tremor, cardiac abnormalities and seizures.

No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

80155

Components
Component Test Code* Component Chart Name LOINC
2011608 Caffeine, Serum or Plasma 3422-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Caffeine Citrate Injection
  • Durvitan
  • NoDoz
  • Vivarin
Caffeine, Serum or Plasma