Optimize drug therapy and monitor patient adherence.
Quantitative Gas Chromatography/Mass Spectrometry
Serum Pre-dose (Trough) Draw - At a Steady State Concentration or Plasma Pre-dose (Trough) Draw - At a Steady State Concentration in Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA).
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Whole blood. Gel Separator Tubes, Light Blue (Sodium Citrate), or Yellow (SPS or ACD Solution).
Ambient: 3 months; Refrigerated: 3 months; Frozen: 1 year
|Therapeutic Range||Sedation: 1-5 µg/mL
Intracranial Pressure (ICP) Therapy: 25-35 µg/mL
Coma: 10-50 µg/mL
|Toxic Level||Greater than 10 µg/mL|
The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Toxic concentrations may cause respiratory depression, hypotension, coma and death.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
80345 (Alt code: G0480)
|Component Test Code*||Component Chart Name||LOINC|
- pentobarbital blood level