Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
CARIS SP
Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun, Tue, Thu

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Pre-dose (Trough) Draw - At a Steady State Concentration or Plasma Pre-dose (Trough) Draw - At a Steady State Concentration in Plain Red, Lavender (K2EDTA), Lavender (K3EDTA), or Pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Whole blood. Gel Separator Tubes, Light Blue (Sodium Citrate), or Yellow (SPS or ACD Solution).

Remarks
Stability

Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 months

Reference Interval
Test Number
Components
Reference Interval
  Carisoprodol, Serum or Plasma Less than 8.0 µg/mL
Toxic: Greater than or equal to 8.0 µg/mL
  Meprobamate, Serum or Plasma
Dose-Related Range 5.0-20.0 µg/mL
Toxic Greater than 40.0 µg/mL

Interpretive Data

The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Adverse effects may include drowsiness, dizziness and headache.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

80369 (Alt code: G0480)

Components
Component Test Code* Component Chart Name LOINC
2011455 Carisoprodol, Serum or Plasma 3437-1
2011456 Meprobamate, Serum or Plasma 3753-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Carisoprodol
  • Carisoprodol and Metabolite
  • Equanil
  • Meprospan
  • Miltown
  • Rela
  • Sodol
  • Soma
  • Soma Compound
  • Soprodol
  • Soridol
  • Urine
  • Vanadom
Carisoprodol and Meprobamate, Serum or Plasma, Quantitative