ALK (D5F3) by Immunohistochemistry with Reflex to ALK Gene Rearrangements by FISH
Detects ALK fusion proteins (IHC) and ALK gene rearrangements (FISH) in solid tumors.
Immunohistochemistry/Fluorescence in situ Hybridization
1-5 days; 12 days if reflexed
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Protect paraffin block and/or slides from excessive heat. Transport tissue block or 7 unstained (4-micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808 recommended but not required) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min. 4 slides). If sending precut slides, do not oven bake.
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Paraffin block with no tumor tissue remaining; specimens fixed in any fixative other than 10 percent neutral buffered formalin.
Include surgical pathology report.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable.
Refer to report
No compliance statements are in use for this test.
Note: This test includes pathologist interpretation of results. Include surgical pathology report with specimen submitted for testing. Indicate tissue site on requisition. ALK (D5F3) by Immunohistochemistry will reflex to FISH if result is Equivocal or Positive. Additional charges apply.
88342; if reflexed, add 88366
|Component Test Code*||Component Chart Name||LOINC|
|2007325||ALK(D5F3) by IHC Reference Number||57723-9|
|2007327||ALK(D5F3) by IHC Result||35474-6|
- ALK D5F3 antibody staining
- ALK D5F3 staining
- ALK rearrangement by IHC
- ALK rearrangement staining