Ordering Recommendation

Use only to provide evidence of vaccination or prior infection by measles, mumps, rubella and varicella-zoster viruses.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1.0 mL serum to an ARUP standard transport tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Body fluid, CSF, plasma or urine specimens. Contaminated, heat-inactivated, hemolyzed, lipemic, or severely icteric specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Methodology

Semi-Quantitative Chemiluminescent Immunoassay (CLIA)

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
Components
Reference Interval
  Measles Virus (Rubeola) Antibody IgG
13.4 AU/mL or less Negative - No significant level of Measles (Rubeola) IgG antibody detected. This result is not consistent with vaccination (could indicate lack of immune response to vaccination) or exposure to Measles (Rubeola).
13.5-16.4 AU/mL Equivocal - Repeat testing in 7-14 days may be helpful to demonstrate IgG seroconversion.
16.5 AU/mL or greater Positive - IgG antibody to Measles (Rubeola) detected. This result is consistent with vaccination or exposure to Measles (Rubeola).

  Mumps Virus Antibody IgG
8.9 AU/mL or less Negative - No significant level of Mumps IgG antibody detected. This result is not consistent with vaccination (could indicate lack of immune response to vaccination) or exposure to Mumps.
9.0-10.9 AU/mL Equivocal - Repeat testing in 7-14 days may be helpful to demonstrate IgG seroconversion.
11.0 AU/mL or greater Positive - IgG antibody to Mumps detected. This result is consistent with vaccination or exposure to Mumps.

  Rubella Virus Antibody IgG
8.9 IU/mL or less Negative - No significant level of Rubella IgG antibody detected. This result is not consistent with vaccination (could indicate lack of immune response to vaccination) or exposure to Rubella.
9-9.9 IU/mL Equivocal - Repeat testing in 7-14 days may be helpful to demonstrate IgG seroconversion
10 IU/mL or greater Positive - IgG antibody to Rubella detected. This result is consistent with vaccination or exposure to Rubella..

  Varicella-zoster Virus Ab IgG
<=0.99 S/CO Negative - No significant level of detectable varicella-zoster IgG antibody.
>=1.00 S/CO Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection.

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86765; 86735; 86762; 86787

Components

Component Test Code* Component Chart Name LOINC
2011396 Measles Virus (Rubeola) Antibody IgG 7962-4
2011397 Mumps Virus Antibody IgG 7966-5
2011398 Rubella Virus Antibody IgG 8014-3
2011399 Varicella-zoster Virus Ab IgG 8047-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Occupation Screen - MMR/VZV Antibody Assessment Panel, IgG