Ordering Recommendation

Detect Chlamydia trachomatis and Neisseria gonorrhoeae in a variety of specimens. Positive results are confirmed using an alternate nucleic acid target.

Mnemonic
CTNG CONF
Methodology

Qualitative Transcription-Mediated Amplification

Performed

Sun-Sat

Reported

1-10 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

MultiTest Swab or ThinPrep Collection: Patient must be 14 years of age or older.

Collect

Vaginal specimen collected with pink swab from Aptima MultiTest Swab Specimen Collection kit (ARUP supply #55224 PK/50 or #55229 PK/10) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Also acceptable: Cervical or male urethral specimen collected with blue swab from Aptima Unisex Swab Specimen Collection kit (ARUP supply #28907 PK/50 or #54555 PK/10), first catch urine in sterile container or cervical brush in ThinPrep Pap test collection kit.
Refer to "Sample Collection for the Diagnosis of STD" under Specimen Handling at www.aruplab.com for specific specimen collection and transport instructions.

Specimen Preparation

Swab: Place swab in Swab Specimen Transport Tube, break shaft off at scoreline then recap tube.
Urine: Transfer 2 mL urine within 24 hours to Aptima Urine Specimen Transport Tube (ARUP supply #28908 PK/50 or #54556 PK/10) available online through eSupply using ARUP Connect ™ or contact ARUP Client Services at (800) 522-2787. Liquid level must be between fill lines on tube.
ThinPrep: Vortex ThinPrep PreservCyt solution and transfer 1 mL to an Aptima Specimen Transfer Tube (ARUP supply #42711) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. To reduce the potential for contamination, ThinPrep specimens should be poured off, using sterile technique, into the Aptima Specimen Transfer Tube prior to Cytology Testing.

Storage/Transport Temperature

Refrigerated

Unacceptable Conditions

Large white swab included in Aptima Unisex Swab Specimen Collection kit is for preparatory cleaning of the endocervix and is unacceptable for testing. Specimens in any transport media other than indicated above. Specimens in swab transport media without a swab.

Remarks

Specimen source is required.

Stability

MultiTest or Unisex Swab: Ambient: 2 months; Refrigerated: 2 months; Frozen: 1 year
Aptima Urine Specimen Transport Tube: Ambient: 1 month; Refrigerated: 1 month; Frozen: 3 months
Aptima Specimen Transfer Tube: Ambient: 2 weeks; Refrigerated: 1 month; Frozen: 1 year
ThinPrep: Ambient: 1 month; Refrigerated: 1 month; Frozen: Unacceptable

Reference Interval

Negative

Interpretive Data

This test is intended for medical purposes only. It is not intended for the evaluation of suspected sexual abuse or for other medicolegal indications. Refer to the most recent CDC recommendations for patients in whom a false positive result may have adverse psychosocial impact.
Positive results will be confirmed with alternative nucleic acid target assay.

Compliance Category

Depends on Specimen/Source/Method

Note

If Chlamydia trachomatis and/or Neisseria gonorrhoeae by TMA is positive, then Chlamydia and/or Gonorrhea alternate target TMA will be added for confirmation. Additional charges apply.

Hotline History
N/A
CPT Codes

87491; 87591. If reflexed add 87491 or 87591

Components
Component Test Code* Component Chart Name LOINC
0060755 APTIMA Media Type 74384-9
2005507 Specimen Source 31208-2
2011165 C. trachomatis by TMA with Confirm 43304-5
2011166 N. gonorrhoeae by TMA with Confirm 43305-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Chlamydia and Gonorrhea panel with confirmation
  • Chlamydia and Gonorrhea PCR
  • Combo 2
  • CT/GC PCR
  • CT/NG PCR
  • Gonorrhea
  • NAA
  • Nucleic Acid Amplification Test (NAAT)
Chlamydia trachomatis and Neisseria gonorrhoeae (CTNG) by Transcription-Mediated Amplification (TMA) with Reflex to CT/NG Confirmation