N-Methylhistamine, 24-Hour Urine

2011034
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Example Reports
Abnormal
Normal

Ordering Recommendation

Aid in evaluation of patient with allergic signs and symptoms, such as anaphylaxis. May assist when diagnosing and monitoring mast-cell activation disorders or when evaluating histamine production over a longer time frame.

Mnemonic

NMETHYL U

Methodology

Quantitative Liquid Chromatography/Tandem Mass Spectrometry/Colorimetry

Performed

Varies

Reported

3-10 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as these medications increase N-methylhistamine (NMH) levels.

Collect

24-hour urine.

Specimen Preparation

From a well-mixed 24-hour collection transfer 5 mL urine to an ARUP Standard Transport Tube. (Min: 3 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

Refrigerated. Also acceptable: Room temperature or frozen.

Unacceptable Conditions
Remarks

Collection duration and urine volume must be provided for testing. Total collection volume must be greater than 500 mL.

Stability

Ambient: 2 weeks; Refrigerated: 28 days; Frozen: 28 days

Reference Interval

By Report

Interpretive Data



Compliance Category

Performed by non-ARUP Laboratory

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/03/2020
X
N/A

CPT Codes

82542

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Components

Component Test Code* Component Chart Name LOINC
2011035 Collection Duration 13362-9
2011036 Urine Volume 28009-9
2011037 N-Methylhistamine, 24 Hr Urine 44340-8
2011038 Creatinine Concentration, 24 Hr Urine 2161-8
3002790 Creatinine, 24 Hr Urine 2162-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • 1-Methylhistamine
  • Histamine Metabolites
  • Urinary N-Methylhistamine
N-Methylhistamine, 24-Hour Urine

Mayo Clinic Laboratories