Cytogenetic Test Request Form Recommended (ARUP form #43098)
Ordering Recommendation

For detection of copy number alterations and loss of heterozygosity in FFPE specimens from products of conception.


Molecular Inversion Probe Array




14-21 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation

Fetal autopsy or products of conception.

Specimen Preparation

FFPE Fetal tissue: Transport ten slides, each with 5 µm unstained sections or four 20 µm scrolls or tissue block.
OR FFPE villi: Transport one H&E stained slide and ten slides, each with 5 µm unstained sections or tissue block.

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions

Specimens fixed or processed in alternative fixatives or heavy metal fixatives (B-4 or B-5).


Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Reference Interval
Interpretive Data

For detection of copy number alterations and loss of heterozygosity in FFPE specimens.
Refer to report.

Compliance Statement C: For human genetic inheritable conditions and mutations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.


If sending placenta instead of fetal tissue, at least 80% villi for products of conception specimens.

This test must be ordered using Cytogenetic test request form #43098 or through your ARUP interface. Please submit the Patient History for Prenatal Cytogenetics form with the electronic packing list (https://ltd.aruplab.com/Tests/Pdf/65).

Hotline History
CPT Codes

88381; 81229

Component Test Code* Component Chart Name LOINC
2002148 Block ID 57723-9
2010796 Cytogenomic MIP Array FFPE, POC
2010877 EER Cytogenomic MIP Array FFPE, POC 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • aCGH
  • anomalies
  • array CGH
  • Array Comparative Genomic Hybridization
  • birth defects
  • Chromosomal Microarray
  • CMA; CGH
  • Down
  • Down syndrome
  • Edward
  • Edward syndrome
  • MCA; XO; 45,X; 45X
  • Microarray
  • microdeletion
  • microduplication
  • miscarriage
  • monosomy
  • multiple congenital anomalies
  • Patau
  • Patau syndrome
  • product of conception, POC, villi, placenta, fetal loss, fetal demise, abortion, pregnancy loss, sti
  • SAB
  • Single-nucleotide-polymorphism (SNP) array
  • T13; T18; T21
  • tissue
  • trisomy 13
  • Trisomy 18
  • Trisomy 21
  • Turner
  • Turner syndrome
  • Whole Genome Array, formalin-fixed, paraffin-embedded, FFPE
Cytogenomic Molecular Inversion Probe Array, FFPE Tissue - Products of Conception