Aid in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Sun, Mon, Wed, Fri
Protease Inhibitor tube (PPACK; Phe-Pro-Arg-chloromethylketone) (ARUP supply #49662), available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. A winged collection set must be used.
Mix well. Separate from cells within 1 hour of collection. Transfer 1.5 mL plasma to an ARUP Standard Transport Tube. (Min: 0.7 mL)
Frozen. Separate specimens must be submitted when multiple tests are ordered.
Grossly hemolyzed specimens.
After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 months
Effective August 17, 2015
|Under 18 years||Not established||Not established|
|18 years and older||0.0-2.3 pmol/L||0.0-3.4 pmol/L|
Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.
|Component Test Code*||Component Chart Name||LOINC|
|0093016||PTHrP by LC-MS/MS, Plasma||15087-0|
- Humoral Hypercalcemia of Malignancy Factor
- Parathyroid Hormone Related Peptide
- Parathyroid Hormone Related Protein
- Parathyroid Related Polypeptide
- Parathyroid Related Protein
- PTH Related Peptide
- PTH Related Protein
- PTHrP secretion
- PTHRP, Plasma