Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor Resistance, GenoSure (INACTIVE as of 08/17/20: Refer to 3001234 in the August Hotline)
Recommended testing for HCV genotype 1 patients prior to initiating simeprevir therapy.
Polymerase Chain Reaction/Sequencing
Lavender (K2 or K3 EDTA), Plasma Preparation Tube (PPT), or Serum Separator Tube (SST).
Separate from cells within 6 hours of collection. Transfer 3 mL plasma or serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 2 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks
No compliance statements are in use for this test.
Provide the patients HCV genotype (subtype) 1a or 1b. Procedure should be used for patients with HCV genotype (subtype) 1a or 1b and a viral load greater than 2000 IU/mL.
|Component Test Code*||Component Chart Name||LOINC|
|2010648||EER HCV NS3/4A, Genosure||11526-1|
|2010649||Hepatitis C Virus (HCV) Genotype||32286-7|
- Q80K Polymorphism