Ordering Recommendation

Recommended testing for HCV genotype 1 patients prior to initiating simeprevir therapy.

Mnemonic
HCV NS3
Methodology

Polymerase Chain Reaction/Sequencing

Performed

Varies

Reported

7-13 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (K2 or K3 EDTA), Plasma Preparation Tube (PPT), or Serum Separator Tube (SST).

Specimen Preparation

Separate from cells within 6 hours of collection. Transfer 3 mL plasma or serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 2 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

CRITICAL FROZEN.

Unacceptable Conditions
Remarks
Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval

By report

Interpretive Data



No compliance statements are in use for this test.

Note

Provide the patients HCV genotype (subtype) 1a or 1b. Procedure should be used for patients with HCV genotype (subtype) 1a or 1b and a viral load greater than 2000 IU/mL.

Hotline History
N/A
CPT Codes

87900; 87902

Components
Component Test Code* Component Chart Name LOINC
2010648 EER HCV NS3/4A, Genosure 11526-1
2010649 Hepatitis C Virus (HCV) Genotype 32286-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Q80K Polymorphism
Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor Resistance, GenoSure (INACTIVE as of 08/17/20: Refer to 3001234 in the August Hotline)

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