Preferred test for FFPE tissue at time of diagnosis for detecting prognostically important genomic abnormalities in leukemias/lymphomas and solid tumors involving loss/gain of DNA or loss of heterozygosity (LOH). Monitor disease progression and response to therapy.
Molecular Inversion Probe Array
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport 10 slides, each with 5-micron unstained sections or four 20-micron scrolls or tissue block. Tissue block will be returned after testing. Transport tissue in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Specimens fixed or processed in alternative fixatives or heavy metal fixatives (B-4 or B-5).
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
For detection of copy number alterations and loss of heterozygosity in FFPE specimens.
Refer to report.
Laboratory Developed Test (LDT)
Samples must contain a region with at least 50 percent tumor.
|Component Test Code*||Component Chart Name||LOINC|
|2010230||Cytogenomic MIP Array, FFPE||62375-1|
|2010231||EER Cytogenomic MIP Microarray, FFPE||11526-1|
- array CGH
- Array Comparative Genomic Hybridization
- Chromosomal Microarray
- oncology, formalin-fixed, paraffin-embedded, FFPE
- Single-nucleotide-polymorphism (SNP) array
- Whole Genome Array