Ordering Recommendation

Preferred test to follow-up presumptive results. For general screening, Amphetamines Urine Screen with Reflex to Quantitation (2012209) is preferred.




Quantitative Liquid Chromatography-Tandem Mass Spectrometry




1-4 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Random urine.

Specimen Preparation

Transfer 0.5 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Room temperature

Unacceptable Conditions

Specimens exposed to repeated freeze/thaw cycles.


Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years

Reference Interval

Effective November 11, 2018

Drugs Covered Cutoff Concentrations
Amphetamine 50 ng/mL
Methamphetamine 200 ng/mL
Methylenedioxyamphetamine (MDA) 200 ng/mL
Methylenedioxymethamphetamine (Ecstasy, MDMA) 200 ng/mL
Methylenedioxyethylamphetamine (Eve, MDEA) 200 ng/mL
Phentermine 200 ng/mL

Interpretive Data

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry.

Positive cutoff:
200 ng/mL unless specified below:
Amphetamine 50 ng/mL

For medical purposes only; not valid for forensic use.

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory. 

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Compare to Pain Management, MDMA/MDA, Quantitative, with medMATCH, Urine; Pain Management, Amphetamines, with Confirmation with medMATCH, Urine; Pain Management, Amphetamines, Quantitative, with medMATCH, Urine.

Hotline History


CPT Codes

80325; 80359 (Alt code: G0480)


Component Test Code* Component Chart Name LOINC
2010077 Amphetamine, Urn, Quant 19346-6
2010078 Methamphetamine, Urn, Quant 3780-4
2010079 MDA, Urn, Quant 18355-8
2010080 MDMA, Urn, Quant 19570-1
2010081 MDEA, Urn, Quant 27085-0
2010082 Phentermine, Urn, Quant 20557-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Adderall
  • Amphetamine
  • Benzedrine
  • Carbex
  • Deprenyl
  • Desoxyephedrine
  • Desoxyn
  • Dexedrine
  • Dextroamphetamine
  • Ecstasy
  • Eldepryl
  • Emsam
  • Eve
  • Lisdexamfetamine
  • MDA
  • MDEA
  • MDMA
  • Methamphetamine
  • Methedrine
  • Pain Management
  • Paremyd
  • Selegiline
  • Vicks Inhaler
  • Vyvanse
  • XTC
  • Zelapor
Amphetamines, Urine, Quantitative