Ordering Recommendation
May be useful as an independent risk marker for thrombosis associated with APS and related diseases. Consider using when all criteria aPL antibody tests are negative; positive results should be reported to document persistence.
Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Thu
Reported
1-8 days
New York DOH Approval Status
Specimen Required
Serum separator tube. Also acceptable: Blue (sodium citrate).
Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.15 mL)
Refrigerated. Also acceptable: Frozen.
Other body fluids. Contaminated, hemolyzed, grossly icteric, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Available Separately |
Component | Reference Interval |
---|---|---|
2009448 | Phosphatidylserine and Prothrombin IgG | 0-30 Units |
No | Phosphatidylserine and Prothrombin IgM | 0-30 Units |
Interpretive Data
The presence of elevated and persistent aPS/PT IgG and IgM antibodies (with or without lupus anticoagulant activity) may serve as a risk marker of thrombotic events in patients with certain autoimmune diseases, including antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). Strong clinical correlation is recommended for isolated IgM aPS/PT antibody.
FDA
Note
Hotline History
CPT Codes
83516 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2009448 | Phosphatidylserine and Prothrombin IgG | 85359-8 |
2009450 | Phosphatidylserine and Prothrombin IgM | 85358-0 |