May be useful as an independent risk marker for thrombosis associated with APS and related diseases. Consider using when all criteria aPL antibody tests are negative; positive results should be reported to document persistence.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
New York DOH Approval Status
Serum separator tube. Also acceptable: Blue (sodium citrate).
Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.15 mL)
Refrigerated. Also acceptable: Frozen.
Other body fluids. Contaminated, hemolyzed, grossly icteric, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|2009448||Phosphatidylserine and Prothrombin IgG||0-30 Units|
|No||Phosphatidylserine and Prothrombin IgM||0-30 Units|
The presence of elevated and persistent aPS/PT IgG and IgM antibodies (with or without lupus anticoagulant activity) may serve as a risk marker of thrombotic events in patients with certain autoimmune diseases, including antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). Strong clinical correlation is recommended for isolated IgM aPS/PT antibody.
|Component Test Code*||Component Chart Name||LOINC|
|2009448||Phosphatidylserine and Prothrombin IgG||85359-8|
|2009450||Phosphatidylserine and Prothrombin IgM||85358-0|