Ordering Recommendation

May be useful as an independent risk marker for thrombosis associated with antiphospholipid syndrome (APS) and related diseases. Consider using when all criteria aPL antibody tests are negative; positive results should be reported to document persistence.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST) OR lt. blue (sodium citrate)

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum (Min: 0.3 mL) OR 0.5 mL citrate plasma (Min: 0.3 mL) to an ARUP standard transport tube.

Storage/Transport Temperature

Refrigerated. Also acceptable: Frozen.

Unacceptable Conditions

Contaminated, heat-inactivated, clots, fibrin, gross red blood cells, severely lipemic, severely hemolyzed, or severely icteric specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)

Performed

Thu

Reported

1-8 days

Reference Interval

0-30 Units

Interpretive Data

Elevated and persistent aPS/PT IgG antibody (with or without lupus anticoagulant activity) may serve as a risk marker of thrombotic events in patients with certain autoimmune diseases, including antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). 

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

83516

Components

Component Test Code* Component Chart Name LOINC
2009448 Phosphatidylserine and Prothrombin IgG 85359-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Phosphatidylserine and Prothrombin Antibody, IgG