Ordering Recommendation

Preferred test to confirm diagnosis of pulmonary arterial hypertension (PAH), especially in those with a family history of PAH.

Mnemonic
PAH PANEL
Methodology

Massively Parallel Sequencing/Exonic Oligonucleotide-based CGH Microarray

Performed

Varies

Reported

3-6 weeks

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA) or yellow (ACD Solution A or B).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks

Submit the Patient History Form for Pulmonary Arterial Hypertension with the Electronic Packing List.

Stability

Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable

Reference Interval

By report

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Genes tested: ACVRL1, BMPR2, CAV1, EIF2AK4, ENG, KCNA5**, KCNK3, SMAD9

** Deletion/duplication detection is not available for this gene.

Hotline History
N/A
CPT Codes

81405; 81406; 81479

Components
Component Test Code* Component Chart Name LOINC
2009346 PAH Pan. Seq/DelDup, Specimen 31208-2
2009349 PAH Pan. Seq/DelDup, Interp 49014-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • PAH
  • Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension (PAH) Panel, Sequencing and Deletion/Duplication