Ordering Recommendation

Determine in-vitro susceptibility to antifungal agents for fungal organisms.

Mnemonic
MA FUNGAL
Methodology

Broth Microdilution

Performed

Sun-Sat

Reported

2-12 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Actively growing isolate in pure culture.

Specimen Preparation

Transport sealed container with pure culture on agar slant. Place each specimen in individually sealed bag.

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Mixed cultures or non-viable organisms.

Remarks

Isolate identification and specimen source required.

Stability

Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: Unacceptable

Reference Interval

Susceptible, intermediate, SDD (susceptible dose dependent), or resistant.
MICs (minimum inhibitory concentrations) interpretations are based on current CLSI guidelines.
MECs (minimum effective concentration) without interpretation are reported for select mold species only.

Interpretive Data

Refer to report.

No compliance statements are in use for this test.

Note

Vitreal Penetration: NOT expected for the echinocandins.
CSF Penetration: NOT expected for the echinocandins.
Urine Penetration: ONLY fluconazole and flucytosine (note that the lack of detectable urine concentrations does not necessarily preclude use of other drugs when the infection involves the renal parenchyma.)

Selective reporting by organism and source. The following antifungal agents are tested: Amphotericin B, anidulafungin, caspofungin, fluconazole, 5-fluorocytosine, itraconazole, isavuconazole, micafungin, posaconazole, and voriconazole.

Penicillium species MIC will only be tested with ARUP Medical Director approval.

Susceptibility testing for dermatophytes and dimorphic fungi is not performed at ARUP. If requested, isolates will be sent to the Fungus Testing Laboratory, San Antonio, TX. Specify agents to be tested on the susceptibility test requisition form.

Testing is not performed on isolates from environmental sources.

An additional processing fee will be billed for all organisms not submitted in pure culture, as indicated in the specimen requirements.

If species identification is not provided, identification will be performed at ARUP. Additional charges apply.

An additional charge will be added to requests for drug testing not performed at ARUP and require isolate sendout.

Hotline History
N/A
CPT Codes

87186

Components
Component Test Code* Component Chart Name LOINC
2009257 Susceptibility, Fungal (Yeasts & Molds) 29577-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Fungal
  • Fungus
  • MEC
  • MIC
  • Microdilution
  • Mold
  • Mould
  • Susceptibility
  • Yeast
Antimicrobial Susceptibility - Fungal (Yeasts and Molds)