Ordering Recommendation

HIV-1 genotyping provides antiretroviral susceptibility information for protease inhibitors (PI), reverse transcriptase inhibitors (NRTI, NNRTI), and integrase inhibitors. Intended for patients with viral load >1000 copies/mL.


Polymerase Chain Reaction/Sequencing




7-10 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Lavender (EDTA), pink (K2EDTA) or plasma preparation tube.

Specimen Preparation

Separate plasma from cells within 6 hours. Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 3 mL)

Storage/Transport Temperature


Unacceptable Conditions

Serum. Heparinized specimens.


Please submit most recent viral load and test date, if available.


On Cells: Ambient: 6 hours; After separation from Cells: Ambient 24 hours; Refrigerated: 5 days; Frozen: 4 months

Reference Interval
Available Components Reference Interval
Yes (0055670) Human Immunodeficiency Virus 1, Genotype by Sequencing Refer to report
Yes (2004457) HIV-1 Integrase Inhibitor Resistance by Sequencing Refer to report

Interpretive Data

Refer to individual components.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.


This test may be unsuccessful if the plasma HIV-1 RNA viral load is less than 1,000 HIV-1 RNA copies per mL of plasma.

Hotline History
Component Test Code* Component Chart Name LOINC
0051722 HIV-1 Genotype by Sequencing 53798-5
2004458 HIV-1 Integrase Inhib. Resistance, Seq 72560-6
2010245 EER HIV-1 Genotype by Seq for Panel 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • HIV Genotype (Human Immunodeficiency Virus 1, Genotyping), Raltegravir (Isentress{TM}) Resistance (H
HIV1 Genotype and Integrase Inhibitor Resistance by Sequencing