Ordering Recommendation

HIV-1 genotyping provides antiretroviral susceptibility information for protease inhibitors (PI), reverse transcriptase inhibitors (NRTI, NNRTI), and integrase inhibitors. Intended for patients with viral load >1000 copies/mL.




Polymerase Chain Reaction/Sequencing




7-10 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Lavender (EDTA), pink (K2EDTA) or plasma preparation tube.

Specimen Preparation

Separate plasma from cells within 6 hours. Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 3 mL)

Storage/Transport Temperature


Unacceptable Conditions

Serum. Heparinized specimens.


Please submit most recent viral load and test date, if available.


On Cells: Ambient: 6 hours; After separation from Cells: Ambient 24 hours; Refrigerated: 5 days; Frozen: 4 months

Reference Interval

Available Components Reference Interval
Yes (0055670) Human Immunodeficiency Virus 1, Genotype by Sequencing Refer to report
Yes (2004457) HIV-1 Integrase Inhibitor Resistance by Sequencing Refer to report

Interpretive Data

Refer to individual components.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Modified FDA


This test may be unsuccessful if the plasma HIV-1 RNA viral load is less than 1,000 HIV-1 RNA copies per mL of plasma.

Hotline History


CPT Codes

87901; 87906


Component Test Code* Component Chart Name LOINC
0051722 HIV-1 Genotype by Sequencing 53798-5
2004458 HIV-1 Integrase Inhib. Resistance, Seq 72560-6
2010245 EER HIV-1 Genotype by Seq for Panel 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • HIV Genotype (Human Immunodeficiency Virus 1, Genotyping)
  • Raltegravir (Isentress{TM}) Resistance (HIV-1 Integrase Inhibitor Resistance by Sequencing)
HIV1 Genotype and Integrase Inhibitor Resistance by Sequencing (INACTIVE as of 08/16/21: Refer to 3003853 with the August Hotline)