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Encephalitis Panel with Reflex to Herpes Simplex Virus Types 1 and 2 Glycoprotein G-Specific Antibodies, IgG, Serum
2008915
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Ordering Recommendation
Not a preferred test. Refer to relevant test for the specific pathogen suspected.
Mnemonic
ENCEPH
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)/Semi-Quantitative Chemiluminescent Immunoassay (CLIA)
Performed
Sun-Sat
Reported
2-6 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum separator tube.
Specimen Preparation
Transfer 4.0mL serum to an ARUP standard transport tube. (Min: 2.0mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Refer to individual components. CSF (refer to Encephalitis Panel with Reflex to Herpes Simplex Virus Types 1 and 2 Glycoprotein G-Specific Antibodies, IgG, CSF, test code 2008916).
Remarks
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval
| Test Number |
Components |
Reference Interval |
|---|---|---|
| HSV 1 and/or 2 Abs, IgM by ELISA | 0.89 IV or less | |
| West Nile Virus Ab, IgG, Ser | 1.29 IV or less | |
| West Nile Virus Ab, IgM, Ser | 0.89 IV or less | |
| Mumps Virus Antibody, IgM | 0.79 IV or less | |
| Measles, Rubeola, Antibody IgM | 0.79 AU or less | |
| Varicella-Zoster Virus Antibody, IgM | 0.90 ISR or less |
Interpretive Data
| Component | Interpretation |
|---|---|
| Measles (Rubeola) Antibody, IgG | 13.4 AU/mL or less: Negative - No significant level of detectable measles (rubeola) IgG antibody. 13.5-16.4 AU/mL: Equivocal - Repeat testing in 10-14 days may be helpful. 16.5 AU/mL or greater: Positive - IgG antibody to measles (rubeola) detected, which may indicate a current or past exposure/immunization to measles (rubeola). |
| Measles (Rubeola) Antibody, IgM | 0.79 AU or less: Negative - No significant level of IgM antibodies to measles (rubeola) virus detected. 0.80-1.20 AU: Equivocal - Repeat testing in 10-14 days may be helpful. 1.21 AU or greater: Positive - IgM antibodies to measles (rubeola) virus detected. Suggestive of current or recent infection or immunization. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization. |
| Mumps Virus Antibody, IgG | 8.9 AU/mL or less: Negative - No significant level of detectable IgG mumps virus antibody. 9.0-10.9 AU/mL: Equivocal - Repeat testing in 10-14 days may be helpful. 11.0 AU/mL or greater: Positive - IgG antibody to mumps virus detected, which may indicate a current or past exposure/immunization to mumps virus. |
| Mumps Virus Antibody, IgM | 0.79 IV or less: Negative - No significant level of detectable IgM antibody to Mumps virus. 0.80-1.20 IV: Equivocal - Borderline levels of IgM antibody to Mumps virus. Repeat testing in 10-14 days may be helpful. 1.21 IV or greater: Positive - Presence of IgM antibody to Mumps virus detected, which may indicate a current or recent infection. However, low levels of IgM antibody may occasionally persist for more than 12 months post-infection or immunization. |
| Varicella-Zoster Virus Antibody, IgG | 134.9 IV or less: Negative - No significant level of detectable varicella-zoster IgG antibody. 135.0-164.9 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 165.0 IV or greater: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. |
| Varicella-Zoster Virus Antibody, IgM | 0.90 ISR or less: Negative - No significant level of detectable varicella-zoster virus IgM antibody. 0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful. 1.10 ISR or greater: Positive - Significant level of detectable varicella-zoster virus IgM antibody. Indicative of current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization. |
| Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM by ELISA | 0.89 IV or less: Not Detected. 0.90-1.09 IV: Indeterminate - Repeat testing in 10-14 days may be helpful. 1.10 IV or greater: Detected - IgM antibody to HSV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. |
| Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG | 0.89 IV or less: Not Detected. 0.90-1.09 IV: Indeterminate - Repeat testing in 10-14 days may be helpful. 1.10 IV or greater: Detected. |
| West Nile Virus Antibody, IgG by ELISA, Serum | 1.29 IV or less: Negative - No significant level of West Nile virus IgG antibody detected. 1.30-1.49 IV: Equivocal - Questionable presence of West Nile virus IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1.50 IV or greater: Positive - Presence of IgG antibody to West Nile virus detected, suggestive of current or past infection. |
| West Nile Virus Antibody, IgM by ELISA, Serum | 0.89 IV or less: Negative - No significant level of West Nile virus IgM antibody detected. 0.90-1.10 IV: Equivocal - Questionable presence of West Nile virus IgM antibody detected. Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - Presence of IgM antibody to West Nile virus detected, suggestive of current or recent infection. |
Compliance Category
FDA
Note
If HSV 1 and/or 2 IgG is 1.10 IV or greater, then HSV 1 G-Specific IgG and HSV 2 G-Specific IgG will be added. Additional charges apply.
Hotline History
Hotline History
Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
N/A
CPT Codes
86765 x2; 86735 x2; 86787 x2; 86789; 86788; 86694 x2; if reflexed, add 86695; 86696
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0050167 | Varicella-Zoster Virus Ab, IgG | 5403-1 |
| 0050234 | West Nile Virus Ab, IgG, Ser | 38997-3 |
| 0050236 | West Nile Virus Ab, IgM, Ser | 38166-5 |
| 0050286 | HSV Type 1/2 Combined Ab, IgG | 27948-9 |
| 0050380 | Measles, Rubeola, Antibody IgG | 7962-4 |
| 0050390 | Mumps Virus Antibody, IgG | 25418-5 |
| 0050641 | HSV 1 and/or 2 Abs, IgM by ELISA | 41399-7 |
| 0099314 | Varicella-Zoster Virus Antibody, IgM | 5404-9 |
| 0099589 | Mumps Virus Antibody, IgM | 25419-3 |
| 0099597 | Measles, Rubeola, Antibody IgM | 25421-9 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Encephalitis Panel with Reflex to Herpes Simplex Virus Types 1 and 2 Glycoprotein G-Specific Antibodies, IgG, Serum
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