Ordering Recommendation

Identifies and quantifies CD57+/CD3- NK cells.

Mnemonic
CD57
Methodology

Flow Cytometry

Performed

Sun-Sat

Reported

1-3 days
1-3 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Transport 4 mL whole blood. (Min: 0.5 mL) Specimens must be analyzed within 72 hours of collection.

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated.

Unacceptable Conditions

Specimens older than 72 hours. Clotted or hemolyzed specimens.

Remarks
Stability

Ambient: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable

Reference Interval
Available Separately
Components
Reference Interval
No Percent CD57+CD3- (NK Cells) 1-16 percent of lymph
No Abs CD57+CD3- (NK Cells) 21-357 cells/µL

Interpretive Data

This test identifies and quantifies the CD57+/CD3- NK cells. The significance of low CD57+NK values in diagnosing and monitoring chronic Lyme disease is not well established and should be used in conjunction with other diagnostic tests specified in the Centers for Disease Control Lyme Disease case definition.

Compliance Category

Analyte Specific Reagent (ASR)

Note
Hotline History
N/A
CPT Codes

86356 x2

Components
Component Test Code* Component Chart Name LOINC
2008913 % CD57+CD3- (NK Cells) 51286-3
2008914 Abs CD57+CD3- (NK Cells) 50640-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
CD57+ NK Cells, Peripheral Blood by Flow Cytometry