Supersaturation Profile, Urine

2008771
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Supplemental Resources

Ordering Recommendation

Use for kidney stone risk assessment and monitoring; includes interpretation of data. Panel includes calcium, chloride, citric acid, creatinine, magnesium, oxalate, pH, phosphorous, potassium, sodium, sulfate, and uric acid.

Mnemonic

SUPERSAT

Methodology

Quantitative Spectrophotometry/Quantitative Enzymatic Assay/Quantitative Ion-Selective Electrode

Performed

Mon, Wed, Fri

Reported

1-8 days

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation
Collect

24-hour urine. Refrigerate during collection.

Specimen Preparation

Thoroughly mix entire collection (24-hour) in one container. Transport four separate 4 mL aliquots of urine using Calculi Risk/Supersaturation Urine Collection Kit (ARUP supply# 46007). Available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787. Do not exceed 4 mL in tubes. 
Aliquot according to the following specifications:
1st aliquot (pH 2): Transfer 4 mL urine into a Sulfamic Acid Tube. (Min: 4 mL) Mix well. Freeze immediately.
2nd aliquot (pH 2): Transfer 4 mL urine into a Sulfamic Acid Tube. (Min: 4 mL) Mix well. Freeze immediately.
3rd aliquot (pH 9): Transfer 4 mL urine into a Sodium Carbonate Tube. (Min: 4 mL) Mix well. Freeze immediately.
4th aliquot: Transfer 4 mL urine into an Unpreserved Tube. (Min: 4 mL)  Freeze immediately.
If collection kit is unavailable, transport four 4 mL unadjusted aliquots of urine.

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions
Remarks

Record total volume and collection time interval on tube and test request form.

Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval

Test Number
 Components
 Reference Interval
  Calcium, Urine - per 24h
Diet
 Reference Interval (mg/d)
Calcium-free diet 5-40
Low calcium diet (less than 800 mg/d) 50-150
Average calcium diet (about 800 mg/d) 100-250
High calcium diet (greater than 800 mg/d) > 250

  Creatinine, Urine - per 24h
Age
 Male (mg/d)
 Female (mg/d)
3-8 years 140-700 140-700
9-12 years 300-1300 300-1300
13-17 years 500-2300 400-1600
18-50 years 1000-2500 700-1600
51-80 years 800-2100 500-1400
81 years and older 600-2000 400-1300

  Magnesium, Urine per 24h 12-199 mg/d
  Phosphorus, Urine - per 24h 40-1300 mg/d
  Uric Acid, Urine - per 24h 250-750 mg/d
  Citric Acid, Urine - per 24h 18 years and older: 320-1240 mg/d
  Oxalate, Urine - per 24h
Age
 Male (mg/d)
 Female (mg/d)
0-12 years 7-31 7-31
13 years and older 16-49 13-40

  Sodium, Urine - per 24h 51-286 mmol/d
  Potassium, Urine - per 24h 25-125 mmol/d
  Chloride, Urine - per 24h 140-250 mmol/d
  Sulfate, Urine - per 24h 6-30 mmol/d

Interpretive Data

The values determined for this specimen are placed on the chart to indicate the approximate risk associated with the particular concentrations.  Increased risk is to the right of center; decreased risk, to the left.  Relative supersaturation calculated for calcium oxalate, calcium hydrogen phosphate (brushite) and uric acid calculi is displayed.  Relative risk increases from the middle to the right side of this chart.

Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume. For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Compare to StoneRisk Diagnostic Profile

Hotline History

N/A

CPT Codes

82340; 82436; 82507; 84560; 83735; 83945; 84105; 84133; 84300; 84392; 83986

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Components

Component Test Code* Component Chart Name LOINC
0020201 Sodium, Urine - per volume 2955-3
0020202 Potassium, Urine - per volume 2828-2
0020203 Chloride, Urine - per volume 2078-4
0020205 Calcium, Urine - per volume 17862-4
0020206 Calcium, Urine - per 24h 6874-2
0020207 Creatinine, Urine - per volume 2161-8
0020208 Creatinine, Urine - per 24h 2162-6
0020211 Magnesium, Urine - per volume 19124-7
0020212 Magnesium, Urine per 24h 24447-5
0020213 Phosphorus, Urine - per volume 2778-9
0020214 Phosphorus, Urine - per 24h 2779-7
0020218 Uric Acid, Urine - per volume 3086-6
0020219 Uric Acid, Urine - per 24h 3087-4
0020242 Citric Acid, Urine - per 24h 6687-8
0020243 Citric Acid, Urine - per volume 2128-7
0020255 Oxalate, Urine - per 24h 2701-1
0020484 Oxalate, Urine - per volume 2700-3
0020601 Sodium, Urine - per 24h 2956-1
0020602 Potassium, Urine - per 24h 2829-0
0020603 Chloride, Urine - per 24h 2079-2
0081103 Sulfate, Urine - per volume 47780-2
0081104 Sulfate, Urine - per 24h 26889-6
0081190 Urine Supersaturation, CAHPO4 42673-4
0081191 Urine Supersaturation, UA CALC 42678-3
0081192 Urine Supersaturation Interpretation 48767-8
0081194 Urine Supersaturation, CAOX 34736-9
0097110 Total Volume 19153-6
0097111 Hours Collected 30211-7
2008709 pH, Urine 2756-5
2008772 EER Supersaturation Profile, Urine 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Calculi Risk
  • Calculus Risk
  • choride
  • citric aci
  • creatinine
  • Kidney Stone Profile
  • Kidney Stone Risk Assessment
  • magnesium
  • oxalate
  • phosphorus
  • potassium
  • sulfate
  • uric acid
Supersaturation Profile, Urine