Ordering Recommendation

Diagnostic evaluation of pyridoxine responsive seizures.

Mnemonic
PIPECOL U
Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performed

Fri

Reported

4-12 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

It is preferable that collection and handling of specimens for testing follow Critical Frozen guidelines listed under Specimen Preparation and Storage/Transport Temperature fields. However, specimens that have not been treated as a critical frozen may still be acceptable for testing. Please refer to the information in the Stability field. If urine has been refrigerated for up to 24 hours; freeze the specimen immediately and submit for testing

Collect

Random urine. (first morning urine is preferred)

Specimen Preparation

Transfer 1 mL urine to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.3 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions
Remarks

Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g.TPN therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site at https://www.aruplab.com/patienthistory or by contacting ARUP Client Services.

Stability

Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month (Avoid repeated freeze/thaw cycles)

Reference Interval
Age
Reference Interval
0 - 30 days Less than or equal to 19.6 mmol/mol creatinine
1 - 5 months Less than or equal to 12.1 mmol/mol creatinine
6  - 11 months Less than or equal to 7.2 mmol/mol creatinine
Greater than 1 Year Less than or equal to 1.2 mmol/mol creatinine

Interpretive Data

Refer to report.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

82542

Components
Component Test Code* Component Chart Name LOINC
2008132 Creatinine, Urine (Pipecolic) 2161-8
2008134 Pipecolic Acid, Urine 32335-2
2008135 Pipecolic Acid, Urine - Interpretation 48767-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Alpha-aminoadipic semialdehyde, Urine
  • Delta1-piperideine-6-carboxylate 1, Urine
  • Delta1-piperideine-6-carboxylate 2, Urine
  • Pipecolic Acid, Urine
  • Urine pipecolic acid
Pipecolic Acid, Urine