Ordering Recommendation

Preferred reflex screening test for celiac disease and dermatitis herpetiformis. May aid in monitoring adherence to gluten-free diet.




Quantitative Immunoturbidimetry/Semi-Quantitative Enzyme-Linked Immunosorbent Assay//Semi-Quantitative Indirect Fluorescent Antibody




2-6 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 1.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Plasma. Contaminated, hemolyzed, grossly icteric or grossly lipemic specimens.


After separation from cells: Ambient: Unacceptable; Refrigerated: 14 days; Frozen: 6 months (avoid repeated freeze/thaw cycles)

Reference Interval

Effective February 16, 2016

Test Number
Reference Interval
0050340 Immunoglobulin A Effective February 16, 2021
0-2 years: 2-126 mg/dL
3-4 years: 14-212 mg/dL
5-9 years: 52-226 mg/dL
10-14 years: 42-345 mg/dL
15-18 years: 60-349 mg/dL
19 years and older: 68-408 mg/dL

0051689 Celiac Disease Dual Antigen Screen
19 Units or less Negative - No significant level of detectable IgA or IgG antibodies against human tissue transglutaminase or gliadin peptide.
20 Units or greater Positive - Presence of IgA and/or IgG antibodies against human tissue transglutaminase and/or gliadin peptide; suggests possibility of certain gluten sensitive enteropathies such as celiac disease and dermatitis herpetiformis.

0051357 Deamidated Gliadin Peptide (DGP) Antibody, IgA
19 Units or less Negative
20-30 Units Weak Positive
31 Units or greater Positive

0051359 Deamidated Gliadin Peptide (DGP) Antibody, IgG
19 Units or less Negative
20-30 Units Weak Positive
31 Units or greater Positive

0097709 Tissue Transglutaminase (tTG) Antibody, IgA
3 U/mL or less Negative
4-10 U/mL Weak Positive
11 U/mL or greater Positive

0050736 Endomysial Antibody, IgA by IFA Less than 1:10
0056009 Tissue Transglutaminase Antibody, IgG
5 U/mL or less Negative
6-9 U/mL Weak Positive
10 U/mL or greater Positive

Interpretive Data

Refer to report.

Compliance Category



The Celiac Disease Reflexive Cascade begins with Immunoglobulin A. Depending on findings, one or more reflexive tests may be required in order to provide a clinical interpretation. Tests added may include Tissue Transglutaminase Antibody, IgA; Tissue Transglutaminase Antibody, IgG; Endomysial Antibody, IgA by IFA; Deamidated Gliadin Peptide (DGP) Antibody, IgA; Deamidated Glaidin Peptide (DGP) Antibody, IgG; and/or Celiac Disease Dual Antigen Screen. Refer to the Celiac Testing Algorithm found at https://www.arupconsult.com/Algorithms/CeliacDz.pdf. Additional charges apply.

Hotline History


CPT Codes

82784; if reflexed additional CPT codes may apply: 83516; 86231; 86258 x2; 86364 x2


Component Test Code* Component Chart Name LOINC
0050340 Immunoglobulin A 2458-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


Celiac Disease Reflexive Cascade