Ordering RecommendationRecommendations when to order or not order the test. May include related or preferred tests.
Assess donor genotype.
MnemonicUnique test identifier.
STR-AD DON
MethodologyProcess(es) used to perform the test.
Polymerase Chain Reaction/Fragment Analysis
PerformedDays of the week the test is performed.
Sun-Sat
ReportedExpected turnaround time for a result, beginning when ARUP has received the specimen.
5-9 days
New York DOH Approval StatusIndicates test has been approved by the New York State Department of Health.
This test is New York DOH approved.
Specimen Required
Patient Preparation
Post-transplantation results will be compared to pre-transplant recipient and donor genotypes, therefore, donor and recipient samples must be obtained and genotyped before the transplant event occurs.
Collect
Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B). OR Bone marrow in lavender (EDTA). OR Buccal brushes from donor.
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL) OR Transport 1 mL bone marrow. (Min: 1 mL) OR Transport 2 buccal brushes in a sterile, dry tube. (Min: 2 brushes)
Reference IntervalNormal range/expected value(s) for a specific disease state. May also include abnormal ranges.
By report
Interpretive DataBackground information for test. May include disease information, patient result explanation, recommendations, details of testing, associated diseases, explanation of possible patient results.
Background Information for Chimerism, Donor: Indication: Monitoring for bone marrow transplant patients; correlation with clinical status and consideration of the interval between bone marrow transplantation and testing is necessary for proper interpretation of results. Methodology: PCR followed by capillary electrophoresis. Specimens are analyzed using 15 autosomal markers (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, THO1, D13S317, D16S539, D2S1338, D19S433, vWa, TPOX, D18S51, D5S818, and FGA) and one gender marker (amelogenin). Kit Used: AmpFLSTR Identifiler PCR Amplification Kit, Applied Biosystems. Limit of Detection: 2 percent of minor cell population. Diagnostic errors can occur due to rare sequence variations.
Compliance Category
Laboratory Developed Test (LDT)
NoteAdditional information related to the test.
Hotline History
N/A
CPT CodesThe American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
AliasesOther names that describe the test. Synonyms.
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