Motor and Sensory Neuropathy Evaluation with Reflex to Titer and Neuronal Immunoblot
Aid in diagnosis of combined motor/sensory neuropathy when malignancy, other than plasma cell dyscrasia, is suspected.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody/Qualitative Immunoblot
New York DOH Approval Status
Serum separator tube
Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL)
Plasma, CSF, or other body fluids. Contaminated, heat-inactivated, hemolyzed, severely icteric, or lipemic specimens.
Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 1 year
|Asialo-GM1 Antibodies, IgG/IgM||
|GM1 Antibodies, IgG/IgM||
|GD1a Antibodies, IgG/IgM||
|GD1b Antibodies, IgG/IgM||
|GQ1b Antibodies, IgG/IgM||
|0051284||Sulfate-3-Glucuronyl Paragloboside (SGPG) Antibody, IgM||Less than 1.00 IV|
|0051285||Myelin Associated Glycoprotein (MAG) Antibody, IgM||Less than 1000 TU|
|2007961||Paraneoplastic Antibodies (PCCA/ANNA) by IFA with Reflex to Titer and Immunoblot||Effective August 17, 2020
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Purkinje Cell (PCCA) antibody and Neuronal Nuclear (ANNA) antibody IgG are screened by IFA. If the IFA screen is indeterminate, then a Neuronal Nuclear Antibodies (Hu, Ri, Yo, and Tr/DNER) IgG by Immunoblot will be added. If the IFA screen is positive at 1:10 or greater, then a PCCA/ANNA antibodies titer and Neuronal Nuclear Antibodies (Hu, Ri, Yo, and Tr/DNER) IgG by Immunoblot will be added. Additional charges apply.
83516 x7; 86255; if reflexed add 84182 x4 and/or 86256
|Component Test Code*||Component Chart Name||LOINC|
|0051034||Asialo-GM1 Antibodies, IgG/IgM||88723-2|
|0051035||GM1 Antibodies, IgG/IgM||31500-2|
|0051037||GD1a Antibodies, IgG/IgM||88724-0|
|0051038||GD1b Antibodies, IgG/IgM||88730-7|
|0051039||GQ1b Antibodies, IgG/IgM||88729-9|
|0051284||SGPG Antibody, IgM||31666-1|
|0051285||MAG Antibody, IgM Elisa||17314-6|
|2007962||Purkinje Cell/Neuronal Nuclear IgG Scrn||61177-2|