Ordering Recommendation
Aid in diagnosis of a sensory neuropathy when malignancy, other than plasma cell dyscrasia, is suspected.
Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody/Qualitative Immunoblot
Performed
Refer to individual components
Reported
2-9 days
New York DOH Approval Status
Specimen Required
Serum separator tube
Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL)
Refrigerated.
Other body fluids. Contaminated, heat-inactivated, hemolyzed, grossly icteric, or lipemic specimens.
After separation from cells: Ambient: 24 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval
Test Number |
Components |
Reference Interval |
|||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Purkinje Cell/Neuronal Nuclear IgG Scrn | None Detected | ||||||||||||||||
Neuronal Nuclear Antibody (ANNA) IFA Titer, IgG | Less than 1:10 | ||||||||||||||||
Purkinje Cell Antibody, Titer | Less than 1:10 | ||||||||||||||||
3002917 | Neuronal Nuclear Antibodies (Hu, Ri, Yo, Tr/DNER) IgG by Immunoblot, Serum |
|
|||||||||||||||
0051285 | Myelin Associated Glycoprotein (MAG) Antibody, IgM | Less than 1000 TU | |||||||||||||||
0051284 | Sulfate-3-Glucuronyl Paragloboside (SGPG) Antibody, IgM | Less than 1.00 IV |
Interpretive Data
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Purkinje Cell (PCCA) antibody and Neuronal Nuclear (ANNA) antibody IgG are screened by IFA. If the IFA screen is indeterminate, then a Neuronal Nuclear Antibodies (Hu, Ri, Yo, and Tr/DNER) IgG by Immunoblot will be added. If the IFA screen is positive at 1:10 or greater, then a PCCA/ANNA antibodies titer and Neuronal Nuclear Antibodies (Hu, Ri, Yo, and Tr/DNER) IgG by Immunoblot will be added. Additional charges apply.
Hotline History
Hotline History
CPT Codes
83516 x2; 86255; if reflexed add 84182 x4 and/or 86256
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0051284 | SGPG Antibody, IgM | 31666-1 |
0051285 | MAG Antibody, IgM Elisa | 17314-6 |
2007962 | Purkinje Cell/Neuronal Nuclear IgG Scrn | 61177-2 |
Aliases
- ANNA IgG
- MAG IgM
- Neuronal Nucelar IgG Abs
- Purkinje Cell IgG Screen
- Purkinje Cell Titer
- SGPG IgM