Optimize drug therapy and monitor patient adherence.
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Pre-dose (trough) draw - At steady state concentration.
Lavender (EDTA), Pink (K2EDTA), or Plain Red.
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD Solution).
Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 2 weeks
|Therapeutic range - Total (venlafaxine and o-desmethylvenlafaxine)||195-400 ng/mL|
|Toxic range||Not well established|
The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Adverse effects to venlafaxine therapy may include nausea, vomiting, dizziness, tremor and blurred vision.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
80338 (Alt code: G0480)
|Component Test Code*||Component Chart Name||LOINC|
|2007960||Total Venlafaxine and Metabolite S/P||62849-5|
- Effexor XR