Aripiprazole and Metabolite, Serum or Plasma

2007945
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High
Normal

Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic

ARIPIPRAZO

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Wed, Sat

Reported

1-5 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Pre-dose (trough) draw - At steady state concentration.

Collect

Plain Red. Also acceptable: Lavender (EDTA) or Pink (K2EDTA).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Remarks
Stability

Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 2 weeks

Reference Interval

Effective June 7, 2021

Therapeutic Range (Aripiprazole and Dehydroaripiprazole) 150-500 ng/mL
Toxic range (Aripiprazole and Dehydroaripiprazole) Greater than or equal to 1000 ng/mL

Interpretive Data

The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Adverse effects to aripiprazole therapy may include headache, nausea, somnolence and blurred vision.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
06/07/2021
X
X
N/A

CPT Codes

80342 (Alt code: G0480)

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Components

Component Test Code* Component Chart Name LOINC
2007946 Aripiprazole Serum/Plasma 38893-4
2007947 Dehydroaripiprazole, Serum/Plasma
2007948 Total Aripiprazole and Metabolite S/P
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Abilify
Aripiprazole and Metabolite, Serum or Plasma