Rapid Plasma Reagin (RPR) with Reflex to RPR Titer or T. pallidum Antibody by Particle Agglutination
Ordering Recommendation
Order to confirm a reactive treponemal screening test (eg, CIA, EIA) when using the reverse testing algorithm to screen for syphilis.
New York DOH Approval Status
Specimen Required
Serum separator tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.5 mL). Avoid freezing if possible.
Refrigerated.
Contaminated, grossly hemolyzed, grossly lipemic, plasma, CSF, or other body fluids.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Methodology
Semi-Quantitative Particle Agglutination
Performed
Sun-Sat
Reported
1-4 days
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Rapid Plasma Reagin (RPR) | Non Reactive |
Interpretive Data
Component | Interpretation |
---|---|
Rapid Plasma Reagin (RPR) | RPR (+) = Reactive RPR (-) = Nonreactive |
FDA
Note
If RPR is reactive, then a titer to endpoint will be added. If RPR is nonreactive, a TP-PA (MHA) confirmation will be added. Additional charges apply.
Hotline History
Hotline History
CPT Codes
86592 RPR; if reflexed, add (nonreactive) TP-PA 86780 or (reactive) 86593 RPR titer
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050472 | Rapid Plasma Reagin (RPR) | 20507-0 |
Aliases
- Rapid Plasma Reagin (RPR) with MHA-TP Confirmation
- Rapid Plasma Reagin (RPR), Reverse Algorithm, Syphilis Reverse Algorithm
- Rapid Plasma Reagin Reflex to Titer or TPPA
- RPR (Diagnosis) with Reflex to Titer and Confirmatory Testing
- RPR Reflex to TPPA or Titer
- RPR Reverse Algorithm
- RPR with MHA-TP Confirmation
- Syphilis Reverse Testing Algorithm
- Treponema pallidum (Rapid Plasma Reagin) with Reflex to Titer & TP-PA Confirmation