Diagnostic evaluation for peroxisomal disorders (in conjunction with very long chain fatty acids testing) and/or pyridoxine responsive seizures.
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
New York DOH Approval Status
Adults: Fasting specimen preferred.
Infants and children: Draw specimen prior to feeding or 2-3 hours after a meal.
Green (sodium or lithium heparin), lavender (EDTA), plain red, or serum separator tube.
Separate serum/plasma from cells immediately. Transfer 0.5 mL serum/plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.2 mL)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Samples exposed to more than two freeze/thaw cycle.
Clinical information is needed for appropriate interpretation. Submit age, gender, diet (e.g.TPN therapy), drug therapy, and family history on a Biochemical Genetics Patient History Form available at www.aruplab.com/patienthistory or by contacting ARUP Client Services at (800) 522-2787.
After separation from cells: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month
Effective August 19, 2013
|0-12 months||Less than or equal to 5.2 umol/L|
|Greater than 1 year||Less than or equal to 6.3 umol/L|
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2007407||Pipecolic Acid, Serum/Plasma||32334-5|
|2007408||Pipecolic Acid Ser/Plas Interpretation||48767-8|
- Alpha-aminoadipic semialdehyde, serum
- Delta1-piperideine-6-carboxylate, Serum
- Pipecolic Acid, Serum/Plasma