Identify the most common IDH mutation in diffuse gliomas.
Formalin fix (10 percent neutral buffered formalin is preferred) and paraffin embed specimen. Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800)522-2787. (Min. 3 slides) If sending precut slides, do not oven bake.
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Paraffin block with no tumor tissue remaining.
This test code includes pathologist interpretation. Include surgical pathology report. When ordering, please identify tissue site. IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, please contact ARUP Client Services at (800) 522-2787.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2007358||IDH1 R132H Mutation Reference Number|
|2007359||IDH1 R132H Point Mutation by IHC Result|
|3003120||IDH1 Tissue Source|
- Astrocytoma and Oligodendroglioma Tumor Cell Marker
- IDH1 Point mutation IHC
- IDH1 R132H antibody staining
- IDH1 R132H IHC