Ordering Recommendation

Preferred CSF reflex panel for workup of suspected neuroborreliosis.

Mnemonic
LYMECSFR
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Immunoblot

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 6 mL CSF to an ARUP Standard Transport Tube. (Min: 2.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, or hemolyzed specimens.

Remarks
Stability

Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
0099483 Borrelia burgdorferi Antibodies, Total by ELISA, CSF
0.99 LIV or less Negative - Antibody to B. burgdorferi not detected.
1.00-1.20 LIV Equivocal - Repeat testing in 10-14 days may be helpful.
1.21 LIV or greater Positive - Probable presence of antibody to B. burgdorferi detected.

0055259 Borrelia burgdorferi Antibody, IgG by Immunoblot (CSF) Effective August 15, 2011

Negative
0055258 Borrelia burgdorferi Antibody, IgM by Immunoblot (CSF) Effective August 15, 2011

Negative

Interpretive Data

Refer to individual components.

Compliance Category

Modified FDA

Note

If B. burgdorferi total antibodies by ELISA are 1.00 LIV or greater, then B. burgdorferi IgG antibody by immunoblot and IgM antibody by immunoblot will be added. Additional charges apply.

Hotline History
N/A
CPT Codes

86618; if reflexed, add 86617 x2

Components
Component Test Code* Component Chart Name LOINC
0099483 Borrelia burgdorferi Abs, ELISA, CSF 6318-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Lyme Disease CSF Abs Reflex Panel
Borrelia burgdorferi (Lyme Disease) Reflexive Panel (CSF)