Ordering Recommendation

Preferred CSF reflex panel for workup of suspected neuroborreliosis.

Mnemonic

LYMECSFR

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Immunoblot

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 6 mL CSF to an ARUP Standard Transport Tube. (Min: 2.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Bacterially contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.

Remarks
Stability

Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Test Number
Components
Reference Interval
  Borrelia burgdorferi Abs, ELISA, CSF 0.99 LIV or less

Interpretive Data

Refer to individual components.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.


Component
Interpretation
Borrelia burgdorferi Antibodies, Total by ELISA, CSF 0.99 LIV or less:  Negative - Antibody to B. burgdorferi not detected.
1.00-1.20 LIV:  Equivocal - Repeat testing in 10-14 days may be helpful.
1.21 LIV or greater:  Positive - Probable presence of antibody to B. burgdorferi detected.

Compliance Category

Modified FDA

Note

If B. burgdorferi total antibodies by ELISA are 1.00 LIV or greater, then B. burgdorferi IgG antibody by immunoblot and IgM antibody by immunoblot will be added. Additional charges apply.

Hotline History

N/A

CPT Codes

86618; if reflexed, add 86617 x2

Components

Component Test Code* Component Chart Name LOINC
0099483 Borrelia burgdorferi Abs, ELISA, CSF 6318-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Lyme Disease CSF Abs Reflex Panel
Borrelia burgdorferi (Lyme Disease) Reflexive Panel (CSF)