Ordering Recommendation

Confirm a diagnosis of hairy cell leukemia (HCL) and monitor tumor burden.

Methodology

Polymerase Chain Reaction (PCR)

Performed

Varies

Reported

4-10 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) or bone marrow (EDTA).

Specimen Preparation

Whole Blood: Do not freeze. Transport 5 mL whole blood. (Min: 1 mL)
Bone Marrow: Transport 3 mL bone marrow. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma, serum, FFPE tissue blocks/slides, or frozen tissue. Specimens collected in anticoagulants other than EDTA or sodium heparin. Clotted or grossly hemolyzed specimens.

Remarks
Stability

Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

81210

Components

Component Test Code* Component Chart Name LOINC
2007133 BRAF V600E Detection Hairy Cell, Result 85101-4
2007134 BRAF V600E Detection Hairy Cell, Quant 81258-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • BRAF V600E
  • Hairy cell leukemia BRAF testing
  • Hairy cell leukemia quant PCR
BRAF V600E Mutation Detection in Hairy Cell Leukemia by Real-Time PCR, Quantitative