Cytomegalovirus, Quantitative PCR with Reflex to Drug Resistance Testing by Sequencing
Detect and quantify cytomegalovirus. Determine antiviral drug resistance to cidofovir, foscarnet sodium, and ganciclovir.
Quantitative Polymerase Chain Reaction/Sequencing
Lavender (EDTA) or pink (K2EDTA).
Separate plasma from cells. Transfer 4 mL plasma to a sterile container. (Min: 2.5 mL)
Serum. Heparinized specimens.
Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 1 year
The quantitative range of this test is 2.6 - 6.6 log copies/mL (390-3,900,000 copies/mL) or 2.4 - 6.4 log IU/mL (227- 2,270,000 IU/mL). One IU/mL of CMV DNA is approximately 1.72 copies/mL.
A negative result (less than 2.6 log copies/mL [less than 390 copies/mL] OR less than 2.4 log IU/mL [less than 227 IU/mL]) does not rule out the presence of PCR inhibitors in the patient specimen or CMV DNA concentrations below the level of detection of the test. Inhibition may also lead to underestimation of viral quantitation.
Analyte Specific Reagent (ASR)
If CMV Quantitative PCR result is greater than or equal to 3.2 log (1600 copies/mL), then CMV Antiviral Drug Resistance by Sequencing will be added. Additional charges apply.
87497; if reflexed, add 87910
|Component Test Code*||Component Chart Name||LOINC|
|0051814||Cytomegalovirus Quant by PCR, Interp||40444-2|
|0051815||Cytomegalovirus Quant by PCR, Log Cpy/mL||53763-9|
|2002316||Cytomegalovirus Quant by PCR, Cpy/mL||33006-8|
|2006534||Cytomegalovirus Quant by PCR, IU/mL||34720-3|
|2006535||Cytomegalovirus Quant by PCR, Log IU/mL||72494-8|
- CMV genotype
- CMV Quant PCR Drug Resistance Reflex
- CMV quantitative
- CMV reflex
- Human herpesvirus 5
- Viral load monitoring