Screen for potential SDH germline mutations in patients with certain tumor types.
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport tissue block or 6 unstained (3- to 5- micron thick sections), positively charged slides in a tissue transport kit (ARUP Supply #47808) available online through eSupply using AUP Connect™ or contact ARUP Client Services at (800)522-2787. (Min. 2 slides) If sending precut slides, do not oven bake.
Room temperature or refrigerated. Ship in cooled container during summer months.
Specimens submitted with non-representative tissue type. Depleted specimens.
IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. For additional technical details, please contact ARUP Anatomic Pathology at (801)581-2507.
Ambient: Indefinite; Refrigerated: Indefinitely; Frozen: Unacceptable
Refer to report.
Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
This test code includes pathologist interpretation of results. Include surgical pathology report with specimen submitted for testing. Indicate tissue site on requisition.
|Component Test Code*||Component Chart Name||LOINC|
|2006949||SDHB w/Interp by IHC - Reference Number|
|2006950||SDHB w/Interp by IHC - Tissue Source|
|2006951||SDHB w/Interp by IHC - Result|
- SDHB IHC
- SDHB immunostaining
- Succinate Dehydrogenase B