Ordering Recommendation

Use following an abnormal amniotic fluid alpha fetoprotein (AFP) result to evaluate possibility of a fetal open neural tube defect.

Mnemonic
ACETYL AF
Methodology

Qualitative Gel Electrophoresis/Radial Immunodiffusion

Performed

Mon, Wed

Reported

3-11 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Amniotic Fluid

Specimen Preparation

Transfer 2 mL amniotic fluid to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Ambient.

Unacceptable Conditions
Remarks

Include the Amniotic Fluid AFP and MoM results, if available.

Stability

Ambient: 2 months; Refrigerated: 4 months; Frozen: 3 years

Reference Interval

Acetylcholinesterase: Negative
Fetal Hemoglobin: Negative

Interpretive Data

Refer to report

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

82013; 83033

Components
Component Test Code* Component Chart Name LOINC
2006849 Acetylcholinesterase, Amniotic Fluid 30106-9
2006850 Fetal Hemoglobin, Amniotic Fluid 28067-7
2006853 Acetylcholinesterase/Fetal HGB Interp 48767-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Acetylcholinesterase Amniotic Fluid AFP
  • Acetylcholinesterase, AF
  • Acetylcholinesterase, Amniotic Fluid
  • AChE-AF
  • Amniotic Fluid, Acetylcholinesterase
  • Fetal Hemoglobin, Amniotic Fluid
Acetylcholinesterase and Fetal Hemoglobin, Amniotic Fluid