Recommended test for the surveillance of residual/recurrent thyroid cancer. Accurately measures thyroglobulin levels in serum or plasma.
Quantitative Chemiluminescent Immunoassay/High Performance Liquid Chromatography-Tandem Mass Spectrometry
New York DOH Approval Status
Serum Separator Tube (SST). Also acceptable: Green (Sodium or Lithium Heparin).
Transfer 3 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL)
EDTA or K2EDTA plasma. Grossly lipemic samples. Any fluid other than noted above. (See Thyroglobulin, Fine Needle Aspiration (FNA) (ARUP test code 0020753) for ordering alternate fluids).
After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 6 months
|Thyroglobulin Antibody||0.0-4.0 IU/mL|
|Thyroglobulin, Serum or Plasma||
|Thyroglobulin by LC-MS/MS, Serum/Plasma||
Specimens negative for thyroglobulin antibodies (TgAb) are tested for thyroglobulin (Tg) by chemiluminescent immunoassay (CIA) using the Beckman Coulter Access DxI method. Specimens with TgAb results above the upper reference limit are tested for Tg by high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). Results obtained with different test methods or kits cannot be used interchangeably. Tg results, regardless of concentration, should not be interpreted as absolute evidence for the presence or absence of papillary or follicular thyroid cancer. Tg testing is not recommended for use as a screening procedure to detect the presence of thyroid cancer in the general population.
Lower limit of detection for Thyroglobulin by LC-MS/MS is 0.5 ng/mL.
The reflex testing method (CIA or LC-MS/MS) is determined by the TgAb result. Additional charges apply.
86800; if reflexed, add 84432
|Component Test Code*||Component Chart Name||LOINC|
|0070420||Thyroglobulin, Serum or Plasma||3013-0|
|2007078||Thyroglobulin by LC-MS/MS, Serum/Plasma||3013-0|
- Anti Thyroglobulin Antibody
- Human Thyroglobulin
- Thyroglobulin Antibody
- Thyroglobulin Assay for Thyroid Cancer
- Thyroglobulin HTC