Thyroglobulin by LC-MS/MS, Serum or Plasma

2006550
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Additional Technical Information

Ordering Recommendation

Recommended test for quantifying thyroglobulin in individuals with antithyroglobulin antibodies. Aids in surveillance of residual/recurrent thyroid cancer in individuals who have developed antibodies to thyroglobulin.

Mnemonic

THYROG MS

Methodology

High Performance Liquid Chromatography-Tandem Mass Spectrometry

Performed

Mon, Wed, Thu, Sat

Reported

1-6 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube or green (sodium or lithium heparin), Potassium EDTA

Specimen Preparation

Separate from cells: Transport 1.5 mL serum or plasma. (Min: 0.7 mL)

Storage/Transport Temperature

Refrigerated or Frozen.

Unacceptable Conditions

Samples left ambient for greater than 1 day; Grossly lipemic samples.

Remarks
Stability

After separation from cells: Ambient: 1 day; Refrigerated: 1 week; Frozen: 1 year

Reference Interval

Age
 Reference Interval
6 months - 3 years 7.4 - 48.7 ng/mL
4 - 7 years 4.1 - 40.5 ng/mL
8 - 17 years 0.8 - 29.4 ng/mL
18 years and older 1.3 - 31.8 ng/mL

Interpretive Data

Lower limit of detection for Thyroglobulin by LC-MS/MS is 0.5 ng/mL.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
05/16/2022
X
N/A

CPT Codes

84432

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Components

Component Test Code* Component Chart Name LOINC
2007078 Thyroglobulin by LC-MS/MS, Serum/Plasma 3013-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Thyroglobulin by LC-MS/MS, Serum or Plasma