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Thyroglobulin by LC-MS/MS, Serum or Plasma
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Ordering Recommendation
Recommended test for quantifying thyroglobulin in individuals with antithyroglobulin antibodies. Aids in surveillance of residual/recurrent thyroid cancer in individuals who have developed antibodies to thyroglobulin.
Mnemonic
Methodology
High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Mon, Wed, Thu, Sat
Reported
1-6 days
New York DOH Approval Status
Specimen Required
Serum separator tube or green (sodium or lithium heparin), Potassium EDTA
Separate from cells: Transport 1.5 mL serum or plasma. (Min: 0.7 mL)
Refrigerated or Frozen.
Samples left ambient for greater than 1 day; Grossly lipemic samples.
After separation from cells: Ambient: 1 day; Refrigerated: 1 week; Frozen: 1 year
Reference Interval
| Age |
Reference Interval |
|---|---|
| 6 months - 3 years | 7.4 - 48.7 ng/mL |
| 4 - 7 years | 4.1 - 40.5 ng/mL |
| 8 - 17 years | 0.8 - 29.4 ng/mL |
| 18 years and older | 1.3 - 31.8 ng/mL |
Interpretive Data
Lower limit of detection for Thyroglobulin by LC-MS/MS is 0.5 ng/mL.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
84432
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2007078 | Thyroglobulin by LC-MS/MS, Serum/Plasma | 3013-0 |
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