Ordering Recommendation

Recommended test for quantifying thyroglobulin in individuals with antithyroglobulin antibodies. Aids in surveillance of residual/recurrent thyroid cancer in individuals who have developed antibodies to thyroglobulin.

Mnemonic
THYROG MS
Methodology

High Performance Liquid Chromatography-Tandem Mass Spectrometry

Performed

Mon, Wed, Thu, Sat

Reported

1-6 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube or green (sodium or lithium heparin), Potassium EDTA

Specimen Preparation

Separate from cells: Transport 1.5 mL serum or plasma. (Min: 0.7 mL)

Storage/Transport Temperature

Refrigerated or Frozen.

Unacceptable Conditions

Samples left ambient for greater than 1 day

Remarks
Stability

After separation from cells: Ambient: 1 day; Refrigerated: 1 week; Frozen: 1 year

Reference Interval
Age
Reference Interval
6 months - 3 years 7.4 - 48.7 ng/mL
4 - 7 years 4.1 - 40.5 ng/mL
8 - 17 years 0.8 - 29.4 ng/mL
18 years and older 1.3 - 31.8 ng/mL

Interpretive Data

Lower limit of detection for Thyroglobulin by LC-MS/MS is 0.5 ng/mL.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

84432

Components
Component Test Code* Component Chart Name LOINC
2007078 Thyroglobulin by LC-MS/MS, Serum/Plasma 3013-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Thyroglobulin by LC-MS/MS, Serum or Plasma