Ordering Recommendation

Molecular diagnostics are preferred for suspected invasive CMV.

Mnemonic
V VIC R
Methodology

Cell Culture/Immunofluorescence

Performed

Sun-Sat

Reported

Viral Culture: 3-16 days
Cytomegalovirus Rapid Culture: 1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Bronchoalveolar lavage (BAL), nasopharyngeal aspirate, swab, or washing, or tracheal aspirate, sputum, throat, tissue (lung, etc.).

Specimen Preparation

Fluid: Transfer 3 mL specimen to a sterile container. (Min: 0.5 mL) Also acceptable: Transfer to 3 mL viral transport media (ARUP Supply #12884) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Swab or Tissue:
Place in 3 mL viral transport media (ARUP Supply #12884) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Calcium alginate, eSwab, dry, or wood swabs.

Remarks

Specimen source preferred.

Stability

Ambient: 2 hours; Refrigerated: 72 hours; Frozen: Unacceptable

Reference Interval

Negative.

Interpretive Data

Refer to Report.

No compliance statements are in use for this test.

Note

Identification is billed separately from culture. Viruses that can be isolated include adenovirus; cytomegalovirus; enterovirus; herpes simplex virus; influenza A and B; parainfluenza types 1, 2, 3; RSV; and varicella-zoster virus. However, virus-specific tests are recommended and are listed below.

The following test is standard-of-care for diagnosing Adenovirus infection in tissue specimens:
Adenovirus by Qualitative PCR (ARUP test code 2007473)

The following tests are recommended for detecting a specific virus in specimens other than CSF. If a specific virus is suspected, please indicate the virus on the test request.

Cytomegalovirus. Refer to Cytomegalovirus Rapid Culture (ARUP test code 0065004)
Human metapneumovirus (hMPV). hMPV can be detected by DFA staining or nucleic acid testing. Refer to Human Metapneumovirus by DFA (ARUP test code 0060779) and Respiratory Viruses DFA (ARUP test code 0060289), or Human Metapneumovirus by PCR (ARUP test code 0060784)
Measles virus. Refer to Measles (Rubeola) Virus Culture (ARUP test code 0065055)
Mumps virus. Refer to Mumps Virus by PCR (ARUP test code 3000523)
Respiratory syncytial virus (RSV). Refer to Respiratory Syncytial Virus DFA (ARUP test code 0060288)
Respiratory viruses. Refer to Respiratory Viruses DFA Stain, ARUP test code 0060289)
Varicella-zoster virus. Refer to Varicella-Zoster Virus DFA with Reflex to Varicella-Zoster Virus Culture (ARUP test code 0060282)

Hotline History
N/A
CPT Codes

87252; 87254; If definitive identification required, add 87253.

Components
Component Test Code* Component Chart Name LOINC
2006497 Viral Culture, Resp and CMV Culture 6584-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Adenovirus Culture
  • CMV culture
  • CMV rapid culture
  • culture for virus
  • cytomegalovirus
  • enterovirus
  • herpes simplex virus
  • HSV culture
  • influenza A and B
  • parainfluenza types 1, 2, 3
  • RSV culture
  • varicella-zoster virus
  • VSV culture
Viral Culture, Respiratory and Cytomegalovirus Rapid Culture