Use to detect IDH1 and IDH2 mutations in whole blood or bone marrow. May have prognostic significance in patients with hematologic malignancies, depending on the clinical and genetic context. For FFPE tissues, use IDH1 and IDH2 Mutation Analysis Exon 4, Formalin-Fixed, Paraffin-Embedded (FFPE) Tissue (3004267).
Polymerase Chain Reaction/Sequencing
Sun, Tue, Thur
New York DOH Approval Status
Lavender (EDTA) or bone marrow (EDTA).
Whole Blood: Do not freeze. Transport 5 mL whole blood. (Min: 1 mL)
Bone Marrow: Do not freeze. Transport 3 mL bone marrow. (Min: 1 mL)
Plasma, serum, FFPE tissue blocks/slides, or frozen tissue, DNA extracted by a non-CLIA lab. Specimens collected in anticoagulants other than EDTA or sodium heparin. Clotted or grossly hemolyzed specimens.
Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2006445||IDH1 and IDH2 Mutation Results||35474-6|
|2006510||IDH 1-2 Source||66746-9|
- IDH1 SNP
- Isocitrate dehydrogenase (IDH) 1 and 2
- Isocitrate Dehydrogenase 1
- Isocitrate Dehydrogenase 2