Ordering Recommendation

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum separator tube. Multiple specimen tubes should be avoided.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 2.05 mL serum to an ARUP Standard Transport Tube. (Min: 1.00 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Test Number
Components
Reference Interval
  Immunoglobulin E
Age Reference Interval (kU/L)
0-5 months 13 or less
6-12 months 34 or less
1-2 years 97 or less
3 years 199 or less
4-6 years 307 or less
7-8 years 403 or less
9-12 years 696 or less
13-15 years 629 or less
16-17 years 537 or less
18 years and older 214 or less

  Allergen, Fungi/Mold, A. alternata IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Cat Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Mountain Cedar Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Cottonwood Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Kochia/Firebush IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Pigweed IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Sagebrush/Wormwood IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Timothy Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Western Ragweed IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, Hormodendrum IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Oak Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, A. fumigatus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. pteronyssinus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. farinae IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, White Pine Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Olive Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Dog Dander IgE Less than or equal to 0.34 kU/L

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.


Reporting Range (reported in kU/L) Probability of IgE Mediated Clinical Reaction Class Scoring
Less than 0.10 No significant level detected 0
0.10-0.34 Clinical relevance undetermined 0/1
0.35-0.70 Low 1
0.71-3.50 Moderate 2
3.51-17.50 High 3
17.51 - 50.00 Very high 4
50.01 - 100.00 Very high 5
Greater than 100.00 Very high 6

Compliance Category

FDA

Note

Allergens included in this panel: Alternaria alternata (tenuis), Aspergillus fumigatus, Cat Dander, Cottonwood Tree, D. farinae (mites), D. pteronyssinus (mites), Dog Dander, Hormodendrum (Cladosporium), Kochia/Firebush, Mountain Cedar (Juniper) Tree, Oak Tree, Olive Tree, Pigweed, Sagebrush/Wormwood, Timothy Grass, Western Ragweed, White Pine Tree, and IgE Serum Total.

Hotline History

N/A

CPT Codes

86003 x17; 82785

Components

Component Test Code* Component Chart Name LOINC
0050345 Immunoglobulin E 19113-0
0055001 Allergen, Fungi/Mold, A. alternata IgE 6020-2
0055006 Allergen, Animal, Cat Dander IgE 6833-8
0055007 Allergen, Tree, Mountain Cedar Tree IgE 6178-8
0055010 Allergen, Tree, Cottonwood Tree IgE 6090-5
0055018 Allergen, Weed, Kochia/Firebush IgE 6118-4
0055025 Allergen, Weed, Pigweed IgE 7604-2
0055029 Allergen, Weed, Sagebrush/Wormwood IgE 6286-9
0055032 Allergen, Grass, Timothy Grass IgE 6265-3
0055035 Allergen, Weed, Western Ragweed IgE 6275-2
0055038 Allergen, Fungi/Mold, Hormodendrum IgE 6075-6
0055041 Allergen, Interp, Immunocap Score IgE 48767-8
0055045 Allergen, Tree, Oak Tree IgE 6189-5
0055061 Allergen, Fungi/Mold, A. fumigatus IgE 6025-1
0055063 Allergen, Mites, D. pteronyssinus IgE 6096-2
0055064 Allergen, Mites, D. farinae IgE 6095-4
0055082 Allergen, Tree, White Pine Tree IgE 6282-8
0055155 Allergen, Tree, Olive Tree IgE 6192-9
0099568 Allergen, Animal, Dog Dander IgE 6098-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Allergens, Inhalants, Western Environmental IgE