Ordering Recommendation

Preferred test for fresh specimens at time of diagnosis for detecting prognostically important genomic abnormalities in leukemias/lymphomas and solid tumors involving loss/gain of DNA or loss of heterozygosity (LOH). Monitor disease progression and response to therapy.

Mnemonic
CMA ONC
Methodology

Genomic Microarray (Oligo-SNP Array)

Performed

Sun-Sat

Reported

10-14 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

Green (sodium heparin). Bone marrow or peripheral blood required.

Specimen Preparation

Transport 3 mL bone marrow. (Min: 1 mL) or 5 mL peripheral blood (Min: 2 mL)

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Frozen specimens. Clotted specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable

Reference Interval
Interpretive Data

Refer to report

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note

This test must be ordered using a Cytogenetic test request form 43099 or through your ARUP interface.

Hotline History
N/A
CPT Codes

81277

Components
Component Test Code* Component Chart Name LOINC
2006326 Cytogenomic Microarray SNP - Oncology
2006327 EER CMA ONC 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • genomic microarray, oligo-SNP array
Cytogenomic SNP Microarray - Oncology