Ordering Recommendation

Preferred first-line test to diagnose inherited or acquired factor XIII (FXIII) deficiency. Appropriate for evaluation of patients with a bleeding disorder who present with normal prothrombin time (PT), activated partial thromboplastin​ time (aPTT), and platelet count test results. Monitor FXIII therapy and confirm abnormalities detected on FXIII qualitative assay.

F13 A

Chromogenic Assay




1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Lt. blue (sodium citrate). Refer to Specimen Handling at www.aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum. EDTA plasma, clotted or hemolyzed specimens.


Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: at -20°C or below: 1 month; Frozen at -70°C or below: 3 months

Reference Interval

Factor XIII Activity 69-143%

Interpretive Data

Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
CPT Codes


Component Test Code* Component Chart Name LOINC
2006183 Factor XIII Activity 27815-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Factor 13
  • fibrin stabilizing factor
Factor XIII Activity