Ordering Recommendation

Direct measure of free estradiol in serum. Most accurate measure of bioactive estradiol.

Mnemonic
ESDIOL FR
Methodology

Quantitative Equilibrium Dialysis/High Performance Liquid Chromatography-Tandem Mass Spectrometry

Performed

Tue

Reported

2-10 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube or green (sodium or lithium heparin), Red Top, Plasma Separator Tube.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transport 2 mL serum or plasma. (Min: 1.0 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions
Remarks
Stability

After separation from cells: Ambient: unacceptable; Refrigerated: 1 week; Frozen: 6 months

Reference Interval

Effective August 19, 2013

Age/Gender
Reference Interval
Adult Females - 19 years and older: 
   Follicular Stage
   Mid-Cycle Stage
   Luteal Stage
   Post-Menopausal Stage
.
less than 2.4 pg/mL
less than 3.1 pg/mL
less than 2.6 pg/mL
less than or equal to 0.5 pg/mL
Adult Males Does not apply
Children Does not apply

Interpretive Data



Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

82670

Components
Component Test Code* Component Chart Name LOINC
2006161 Free Estradiol by ED/LC-MS/MS 2240-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • High-Sensitivity Free Estradiol
Free Estradiol by ED/LC-MS/MS