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Recommendations when to order or not order the test. May include related or preferred tests.
Use to directly measure free estradiol. May be used to evaluate estradiol status for individuals with protein-binding abnormalities or individuals on hormonal contraception.
Quantitative Equilibrium Dialysis/High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Days of the week the test is performed.
Tue
Reported
Expected turnaround time for a result, beginning when ARUP has received the specimen.
2-10 days
New York DOH Approval Status
Indicates test has been approved by the New York State Department of Health.
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum separator tube or green (sodium or lithium heparin), Red Top, Plasma Separator Tube.
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transport 2 mL serum or plasma. (Min: 1.0 mL)
Storage/Transport Temperature
Frozen.
Unacceptable Conditions
Remarks
Stability
After separation from cells: Ambient: unacceptable; Refrigerated: 1 week; Frozen: 6 months
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Test Number
Components
Reference Interval
Estradiol, Free by Dialysis
Age
Male (pg/mL)
Female (pg/mL)
Children
Not Applicable
Not Applicable
Adult
Not Applicable
19 years and older Follicular Stage: Less than 2.4 pg/mL Mid-Cycle: Less than 3.1 pg/mL Luteal Stage: Less than 2.6 pg/mL Postmenopausal Stage: Less than or eaual to 0.5 pg/mL
Interpretive Data
Background information for test. May include disease information, patient result explanation, recommendations, details of testing, associated diseases, explanation of possible patient results.
No reference intervals have been established for prepubertal females or for cisgender males. For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/2006160.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Compliance Category
Laboratory Developed Test (LDT)
Note
Additional information related to the test.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Other names that describe the test. Synonyms.
High-Sensitivity Free Estradiol
Estradiol, Free, by Dialysis and Mass Spectrometry