Appropriate when there is a significant chance of trisomy. Chromosome studies will identify obvious numerical abnormalities, balanced chromosomal rearrangements, and large deletions/duplications. If chromosomes are normal, then testing reflexes to microarray.
Giemsa Band/Genomic Microarray (Oligo-SNP Array)
Results requiring the completion of microarray testing may exceed the standard TAT
Green (sodium heparin).
Do not freeze or expose to extreme temperatures. Transport 5 mL whole blood. (Min: 2 mL)
Frozen specimens. Clotted specimens.
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Refer to report.
Compliance Statement C: For human genetic inheritable conditions and mutations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
These studies involve culturing of living cells; therefore, turnaround times given represent average times which are subject to multiple variables. After specimen receipt, results are generally available in an average of 10 days with 7-10 additional days required for microarray.
A processing fee will be charged if the client cancels this procedure after the test has been set up
When the result of Chromosome Analysis is "normal," then Genomic Microarray testing will be added. Additional charges apply.
Specimen and completed test request form, including clinical indication, must be received within 48 hours of collection.
Testing on a neonate, 7 days old or younger, will automatically order a preliminary chromosome analysis (intended to identify whole chromosome aneuploidies and large structural rearrangements). This will be reported under the same accession number as the final chromosome report, and is generally available in 2-3 days, if sample quantity and metaphase quality permits. Final results will be available within 5-7 days.
This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Please submit the Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies form with the electronic packing list (https://ltd.aruplab.com/Tests/Pdf/20).
88262; 88230; 88291; if reflexed, add 81229
|Component Test Code*||Component Chart Name||LOINC|
|0097640||Chromosome Analysis, Peripheral Blood||29770-5|
|2006186||EER Chrom Analysis PB w/Rflx to Array||11526-1|
- Array CGH
- Array Comparative Genomic Hybridization
- Chromosomal Microarray
- CMA SNP
- Comparative Genomic Hybridization
- Congenital Array
- Constitutional Array
- Molecular Karyotype
- Oligo Array
- Oligonucleotide Array
- Single-nucleotide-polymorphism (SNP) array
- Targeted Array
- Whole Genome Array