Ordering Recommendation

Alkaline phosphatase may be increased in the CSF of patients with intracranial germ cell tumors. When increased, isoenzyme testing can identify if a heat-stable isoenzyme (ie, germ cell or placental) is present but cannot quantify the amount of activity.

Mnemonic

CSF ALKP I

Methodology

Quantitative Heat Inactivation/Enzymatic

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 2 mL CSF to an ARUP Standard Transport Tube and refrigerate or freeze ASAP or within 2 hours. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated or frozen.

Unacceptable Conditions

Specimens collected in EDTA, potassium oxalate, sodium citrate, or sodium fluoride. Grossly hemolyzed or lipemic specimens

Remarks
Stability

After separation from cells: Ambient: 2 hours; Refrigerated: 1 week; Frozen: 1 month

Reference Interval

Effective January 17, 2012

Total Alkaline Phosphatase: 0-1 U/L

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

84075; 84080

Components

Component Test Code* Component Chart Name LOINC
2005737 CSF Alkaline Phosphatase Total
2005738 CSF Alk Phos Bone Calc
2005739 CSF Alk Phos Liver Calc
2005740 CSF Alk Phos Other Calc
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • ALK PHOS
  • Alkaline Phosphatase
  • Alkp
Alkaline Phosphatase Isoenzymes, CSF