Ordering Recommendation

Alkaline phosphatase may be increased in the CSF of patients with intracranial germ cell tumors. When increased, isoenzyme testing can identify if a heat-stable isoenzyme (ie, germ cell or placental) is present but cannot quantify the amount of activity.

Mnemonic
CSF ALKP I
Methodology

Quantitative Heat Inactivation/Enzymatic

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 2 mL CSF to an ARUP Standard Transport Tube and refrigerate or freeze ASAP or within 2 hours. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated or frozen.

Unacceptable Conditions

Specimens collected in EDTA, potassium oxalate, sodium citrate, or sodium fluoride. Grossly hemolyzed or lipemic specimens

Remarks
Stability

After separation from cells: Ambient: 2 hours; Refrigerated: 1 week; Frozen: 1 month

Reference Interval

Effective January 17, 2012

Total Alkaline Phosphatase: 0-1 U/L

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

84075; 84080

Components
Component Test Code* Component Chart Name LOINC
2005737 CSF Alkaline Phosphatase Total
2005738 CSF Alk Phos Bone Calc
2005739 CSF Alk Phos Liver Calc
2005740 CSF Alk Phos Other Calc
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ALK PHOS
  • Alkaline Phosphatase
  • Alkp
Alkaline Phosphatase Isoenzymes, CSF