Alkaline phosphatase may be increased in the CSF of patients with intracranial germ cell tumors. When increased, isoenzyme testing can identify if a heat-stable isoenzyme (ie, germ cell or placental) is present but cannot quantify the amount of activity.
Quantitative Heat Inactivation/Enzymatic Assay
New York DOH Approval Status
Transfer 2 mL CSF to an ARUP Standard Transport Tube and refrigerate or freeze ASAP or within 2 hours. (Min: 1 mL)
Refrigerated or frozen.
Specimens collected in EDTA, potassium oxalate, sodium citrate, or sodium fluoride. Grossly hemolyzed or lipemic specimens
After separation from cells: Ambient: 2 hours; Refrigerated: 1 week; Frozen: 1 month
Effective January 17, 2012
Total Alkaline Phosphatase: 0-1 U/L
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2005737||CSF Alkaline Phosphatase Total|
|2005738||CSF Alk Phos Bone Calc|
|2005739||CSF Alk Phos Liver Calc|
|2005740||CSF Alk Phos Other Calc|
- ALK PHOS
- Alkaline Phosphatase