Acetylcholine Receptor Antibodies and Striated Muscle Antibodies Reflexive Panels, and Titin Antibody
Acceptable reflexive panel for diagnosing myasthenia gravis. Includes acetylocholine receptor (AChR) binding and blocking antibodies, titin anibodies, and striated muscle antibodies, with possible reflex to AChR modulating antibodies or striated muscle antibody titer.
Quantitative Radioimmunoassay/Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Flow Cytometry
Plain red top or Serum Separator Tube (SST).
Transport 1.5 mL serum. (Min. 0.7 mL) Separate serum from cells ASAP or within one hour of collection. Transfer to an ARUP Standard Transport Tube.
Refrigerated. Frozen is also acceptable.
Plasma. Hemolyzed, lipemic, moderately icteric serum or contaminated specimens.
Repeated freeze-thaw cycles should be avoided.
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
|0080009||Acetylcholine Receptor Binding Antibody||
|0099580||Acetylcholine Receptor Blocking Antibody||Effective November 18, 2013
|0099521||Acetylcholine Receptor Modulating Antibody||Effective August 20, 2012
|2005636||Titin Antibody||Effective January 17, 2012
|0050746||Striated Muscle Antibodies, IgG with Reflex to Titer||Less than 1:40|
Refer to report.
Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.
If Acetylcholine Receptor Binding Antibody result is greater than 0.4 nmol/L or Acetylcholine Receptor Blocking Antibody result is greater than 26 percent, then Acetylcholine Receptor Modulating Antibody will be added. If Striated Muscle Ab is detected, then a titer will be added. Additional charges apply.
83519; 83516 x2; 86255; if reflexed, add 83516 and/or 86256
|Component Test Code*||Component Chart Name||LOINC|
|0050747||Striated Muscle Antibodies, IgG Screen||49692-7|
|0080009||Acetylcholine Binding Antibody||11034-6|
|0099580||Acetylcholine Blocking Antibody||42937-3|
- AChR Binding Antibody
- AChR Antibody
- Anti-Skeletal Muscle IgG Antibodies
- Anti-Striated Antibody
- anti-tintin Ab
- Muscle (Skeletal) Antibodies
- Muscle nicotinic Acetylcholine Receptor
- Myasthenia Gravis Antibodies
- Myoid Antibody
- Skeletal Muscle Antibodies
- Striational Antibodies