Cytogenetic Test Request Form Recommended (ARUP form #43098)

Ordering Recommendation

For use in the context of intrauterine fetal demise or stillbirth when further cytogenetic analysis is desired, pregnancy loss or termination in the presence of fetal anomalies, fetal chromosomal abnormalities that are seen by conventional cytogenetic methods and need further characterization, multiple fetal losses of unknown etiology, or products of conception (POC) specimens that fail to grow in culture.

New York DOH Approval Status

Testing is not New York state approved. Specimens from New York clients will be sent out to a New York state-approved laboratory.

Specimen Required

Patient Preparation

Thaw media prior to tissue inoculation. Products of conception in a sterile, screw-top container (wide-mouth containers: ARUP supply #42710) filled with tissue culture transport medium (ARUP supply #32788). Available online through eSupply using ARUP Connect or contact ARUP Client Services at 800-522-2787. If cytogenetics tissue media is not available, collect in plain RPMI, Hanks solution, sterile saline, or ringers.
If autopsy is performed: Facia lata, diaphragm, tendon, skin, tissue from internal organs (if fresh), chest wall cartilage (particularly if macerated) or placenta from fetal side.
If no autopsy is performed: Placenta from fetal side is preferred (eg, villi).

Also acceptable: Skin (POC), Cord Tissue, Umbilical cord, Decidua, or Achilles tendon.

Specimen Preparation

Do not place in formalin. Transport products of conception, skin (POC), cord tissue, or decidua (min: 5mg) in sterile, screw-top container filled with tissue transport medium. If specimen size is too large for a normal collection tube, a larger sterile container can be used such as a sterile urine cup and can be flooded with several tubes of cytogenetic tissue media.

Storage/Transport Temperature

Room temperature (fresh tissue or culture flask). Also acceptable: Refrigerated or frozen.

Unacceptable Conditions

Intact fetus. Specimens preserved in formalin. Autolyzed or contaminated specimens.
Skin (POC), Decidua: formalin fixed.
Cord Tissue: formalin fixed, decomposed.


If specimen collection time is greater than 72 hours, testing may be compromised. The laboratory will make every attempt to culture the specimen. Send specimen to lab for testing.

NOTE: Decidua is acceptable but represents maternal rather than fetal tissue.


Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Indefinitely


Genomic Microarray (Oligo-SNP Array)




14-21 days

Reference Interval

Interpretive Data

Refer to report.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Compliance Category

Laboratory Developed Test (LDT)


A processing fee will be charged if this procedure is canceled, at the client's request, after the test has been set up.

This test must be ordered using Cytogenetic test request form #43098 or through your ARUP interface. Please submit the Patient History for Prenatal Cytogenetics form with the electronic packing list (https://ltd.aruplab.com/Tests/Pdf/65).

Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
2005634 SNP Microarray, Products of Conception 62375-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • genomic microarray
  • oligo-SNP array
Genomic SNP Microarray, Products of Conception