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Endomysial Antibody, IgG
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Ordering Recommendation
• Acceptable single screening test for IgA-deficient individuals with suspected celiac disease.
• Preferred screening test is Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgG (0056009). (IgA testing recommended to identify IgA deficiency.)
• May aid in monitoring adherence to gluten-free diet in celiac disease confirmed patients.
Mnemonic
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Performed
Tue, Fri
Reported
1-8 days
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
Refrigerated.
Contaminated specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Effective November 14, 2011
Less than 1:10
Interpretive Data
The presence of endomysial antibodies IgG, may be useful in identifying IgA-deficient patients at risk for celiac disease. To establish the diagnosis of celiac disease, a positive result must be confirmed through a biopsy of the small intestine.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
86231
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2005502 | Endomysial Antibody, IgG | 51699-7 |
Aliases
- Anti-Endomysial Antibodies
- EMA
- EMA IgG
- Gluten-Sensitive Enteropathy Tests
- IgA Deficient Celiac Disease
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