Ordering Recommendation

• Acceptable single screening test for IgA-deficient individuals with suspected celiac disease. 
• Preferred screening test is Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgG (0056009).  (IgA testing recommended to identify IgA deficiency.)
• May aid in monitoring adherence to gluten-free diet in celiac disease confirmed patients.


Semi-Quantitative Indirect Fluorescent Antibody


Tue, Fri


1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature


Unacceptable Conditions

Contaminated specimens.


After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Effective November 14, 2011

Less than 1:10

Interpretive Data

The presence of endomysial antibodies IgG, may be useful in identifying IgA-deficient patients at risk for celiac disease. To establish the diagnosis of celiac disease, a positive result must be confirmed through a biopsy of the small intestine.

Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
CPT Codes


Component Test Code* Component Chart Name LOINC
2005502 Endomysial Antibody, IgG 51699-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Anti-Endomysial Antibodies
  • EMA
  • EMA IgG
  • Gluten-Sensitive Enteropathy Tests
  • IgA Deficient Celiac Disease
Endomysial Antibody, IgG